In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs

被引:143
作者
Alcalá, L [1 ]
Ruiz-Serrano, MJ [1 ]
Turégano, CPF [1 ]
Garcia de Viedma, D [1 ]
Díaz-Infantes, M [1 ]
Marín-Arriaza, M [1 ]
Bouza, E [1 ]
机构
[1] Hosp Gen Univ Gregorio Maranon, Serv Microbiol & Enfermedades Infecciosas, Madrid 28007, Spain
关键词
D O I
10.1128/AAC.47.1.416-417.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We evaluated 117 isolates of Mycobacterium tuberculosis for susceptibility to linezolid by the proportion and E-test methods. Linezolid showed high in vitro activity, with all the strains inhibited by less than or equal to1 mug of the drug per ml. E-test MICs were at least 4 dilutions lower than their equivalents by the standard proportion method.
引用
收藏
页码:416 / 417
页数:2
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