Preparation and characterization of nano-sized hydroxyapatite particles and hydroxyapatite/chitosan nano-composite for use in biomedical materials

被引：268

作者：

Chen, F

Wang, ZC

Lin, CJ ^{[1
]}

机构：

[1] Xiamen Univ, Dept Chem, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China

[2] Xiamen Univ, Dept Mat Sci & Engn, Xiamen 361005, Peoples R China

来源：

MATERIALS LETTERS | 2002年 / 57卷 / 04期

基金：

中国国家自然科学基金;

关键词：

hydroxyapatite; chitosan; nano-sized; particles; fibers; composite;

D O I：

10.1016/S0167-577X(02)00885-6

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Natural bone is actually an inorganic/organic composite mainly made up of nano-structure hydroxyapatite (Ca-10(PO4)(6)(OH)(2), HAp) and collagen fibers. It is of most importance to synthesize nano-composites of inorganic/organic in order to have good biocompatibility, high bioactivity and great bonding properties. In this work, HAp nano-particle and HAp/chitosan (CTS) nanocomposite with a homogeneous microstructure were prepared and characterized. It is proposed that the nano-structure of hydroxyapatite/chitosan composite will have the best biomedical properties in the biomaterials applications. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：858 / 861

页数：4

共 13 条

[1] Preparation of a porous hydroxyapatite/collagen nanocomposite using glutaraldehyde as a crosslinkage agent [J].