Synthesis and Biological Assessment of Carbazole Linked Pyrazole Schiff bases and Diarylthiourea Derivatives

被引：1

作者：

Shirole, Gopinath D. ^{[1
]}

Pandhare, Gajanan R. ^{[2
]}

Gadhave, Anil G. ^{[2
]}

Uphade, Bhagawat K. ^{[2
]}

Aute, Dilip S. ^{[3
]}

Kadnor, Vijay A. ^{[3
]}

机构：

[1] ASC Coll Rahata, Dept Chem, Ahmednagar 423107, MS, India

[2] Padmashri Vikhe Patil Coll Arts Sci & Commerce, Pravaranagar 413713, MS, India

[3] ACS Coll Satral, Dept Chem, Ahmednagar 413711, MS, India

来源：

CROATICA CHEMICA ACTA | 2020年 / 93卷 / 02期

关键词：

antimicrobial; antimalarial activities; carbazole; diarylthiourea; Schiff base; ANALOGS; UREA; DISCOVERY; DESIGN;

D O I：

10.5562/cca3700

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, (E)-9-ethyl-N-((1,3-diphenyl-1H-pyrazol-4-ylmethylene)-9H-carbazol-3-amine (3a-f) and 1-(9-ethyl-9H-carbazol-6-yl)-3-phenylthiourea (5a-f) derivatives were synthesized and their in vitro antimicrobial and antimalarial activities were evaluated. The structures of the synthesized compounds were elucidated and confirmed by using IR, H-1 NMR, C-13 NMR, and mass spectra.

引用

页码：139 / 146

页数：8

共 50 条

[41] Pyrazole acylhydrazone Schiff bases as magnesium alloy corrosion inhibitor: Synthesis, properties and mechanism investigation [J].

Ma, Danyang ;

Zhao, Jianfeng ;

Huang, Qiushuo ;

Li, Guihui ;

Liu, Junxia ;

Ren, Tiegang .

JOURNAL OF MOLECULAR STRUCTURE, 2023, 1281

[42] Synthesis and Biological Evaluation of Novel Pyrazole Derivatives as Anti-Inflammatory Antimicrobial Agents [J].

Bekhit, Adnan A. ;

Ashour, Hayam M. A. ;

Bekhit, Alaa El-Din A. ;

Bekhit, Salma A. .

MEDICINAL CHEMISTRY, 2009, 5 (02) :103-117

[43] Synthesis and biological activities of some new thiazolidine derivatives containing pyrazole ring system [J].

Nishida, Sho ;

Maruoka, Hiroshi ;

Yoshimura, Yuki ;

Goto, Takao ;

Tomita, Ryoko ;

Masumoto, Eiichi ;

Okabe, Fumi ;

Yamagata, Kenji ;

Fujioka, Toshihiro .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2012, 49 (02) :303-309

[44] Synthesis and Biological Activities of Novel Pyrazole Amide Derivatives Containing Substituted Isoxazole Group [J].

Dai, Hong ;

Yao, Wei ;

Ye, Linyu ;

Fang, Yuan ;

Shi, Yujun ;

Song, Chan ;

Li, Chunjian ;

Shi, Jian .

CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 37 (08) :2165-2171

[45] Synthesis, Characterization, and Biological Activity of Organotin(IV) Complexes with Schiff Bases [J].

S. Nazneen ;

S. Ali ;

S. Shahzadi ;

S. Shujah .

Russian Journal of General Chemistry, 2017, 87 :2970-2978

[46] Synthesis and pharmacological activities of hydrazones, Schiff and mannich bases of isatin derivatives [J].

Sridhar, SK ;

Ramesh, A .

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2001, 24 (10) :1149-1152

[47] Synthesis and antibacterial screening of hydrazones, Schiff and Mannich bases of isatin derivatives [J].

Sridhar, SK ;

Saravanan, M ;

Ramesh, A .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2001, 36 (7-8) :615-625

[48] Synthesis, Characterization, and Biological Activity of Organotin(IV) Complexes with Schiff Bases [J].

Nazneen, S. ;

Ali, S. ;

Shahzadi, S. ;

Shujah, S. .

RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2017, 87 (12) :2970-2978

[49] Catalyst-free synthesis of pyrazole-aniline linked coumarin derivatives and their antimicrobial evaluation [J].

Kovvuri, Jeshma ;

Nagaraju, Burri ;

Kumar, C. Ganesh ;

Sirisha, K. ;

Chandrasekhar, Cheemalamarri ;

Alarifi, Abdullah ;

Kamal, Ahmed .

JOURNAL OF SAUDI CHEMICAL SOCIETY, 2018, 22 (06) :665-677

[50] Synthesis, Characterization, Computational and Biological Activity of Some Schiff Bases and Their Fe, Cu and Zn Complexes [J].

Al-Shboul, Tareq M. A. ;

El-khateeb, Mohammad ;

Obeidat, Zaid H. ;

Ababneh, Taher S. ;

Al-Tarawneh, Suha S. ;

Al Zoubi, Mazhar S. ;

Alshaer, Walhan ;

Abu Seni, Anas ;

Qasem, Taqwa ;

Moriyama, Hayato ;

Yoshida, Yukihiro ;

Kitagawa, Hiroshi ;

Jazzazi, Taghreed M. A. .

INORGANICS, 2022, 10 (08)

← 1 2 3 4 5 →