Synthesis and Biological Assessment of Carbazole Linked Pyrazole Schiff bases and Diarylthiourea Derivatives

被引：1
|
作者：
Shirole, Gopinath D. [1 ]
Pandhare, Gajanan R. [2 ]
Gadhave, Anil G. [2 ]
Uphade, Bhagawat K. [2 ]
Aute, Dilip S. [3 ]
Kadnor, Vijay A. [3 ]
机构：
[1] ASC Coll Rahata, Dept Chem, Ahmednagar 423107, MS, India
[2] Padmashri Vikhe Patil Coll Arts Sci & Commerce, Pravaranagar 413713, MS, India
[3] ACS Coll Satral, Dept Chem, Ahmednagar 413711, MS, India
来源：
CROATICA CHEMICA ACTA | 2020年 / 93卷 / 02期
关键词：
antimicrobial; antimalarial activities; carbazole; diarylthiourea; Schiff base; ANALOGS; UREA; DISCOVERY; DESIGN;
D O I：
10.5562/cca3700
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this study, (E)-9-ethyl-N-((1,3-diphenyl-1H-pyrazol-4-ylmethylene)-9H-carbazol-3-amine (3a-f) and 1-(9-ethyl-9H-carbazol-6-yl)-3-phenylthiourea (5a-f) derivatives were synthesized and their in vitro antimicrobial and antimalarial activities were evaluated. The structures of the synthesized compounds were elucidated and confirmed by using IR, H-1 NMR, C-13 NMR, and mass spectra.
引用
收藏
页码：139 / 146
页数：8
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