Active compounds of medicinal plants, mechanism for antioxidant and beneficial effects

被引:40
作者
Montes F, Orozco [1 ]
Vazquez-Hernandez, A. [2 ]
Fenton-Navarro, B. [1 ]
机构
[1] Michoacan Univ St Nicholas Hidalgo UMSNH, Fac Med & Biol Sci Dr Ignacio Chavez, Postgrad Studies Div, Glycobiol Lab, Morelia, Michoacan, Mexico
[2] Hosp Specialties, CMN S21, IMSS, Mexico City, DF, Mexico
关键词
Antioxidants; Free radicals; Secondary metabolites; Polyphenols; Oxidative stress; Medicinal plants; OXIDATIVE STRESS; CARDIOVASCULAR-DISEASE; GUT MICROBIOTA; DIETARY ANTIOXIDANTS; WINE POLYPHENOLS; FREE-RADICALS; EXTRACTS; CANCER; ANTHOCYANINS; BIOSYNTHESIS;
D O I
10.32604/phyton.2019.04525
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
An increased interest in the antioxidant effects of medicinal plants has developed in recent years. Identifying antioxidant compounds present in medicinal plants and elucidating the mechanism by which they prevent oxidation have been the focus of the research community. We performed a systematic and exhaustive review aimed at analyzing the available data regarding the beneficial effects of secondary metabolites in plants. The result of this review is presented as a description of free radicals, as well as cellular and physiological oxidative stress, is provided. The origin and source of antioxidant compounds, and the cellular and molecular mechanism by which they exert antioxidant effects, have been reported. The absorption, distribution and, elimination of antioxidants are mentioned. The beneficial effects of secondary metabolites of medicinal plants in various high incidence disease conditions were also reviewed. Finally, disease states that benefit from antioxidant compounds includes diabetes, cancer, cardiovascular diseases, and liver, brain and, intestinal diseases.
引用
收藏
页码:1 / 10
页数:10
相关论文
共 78 条
  • [1] Review on some antioxidant plants growing in Arab world
    Al-Jaber, Nabilah A.
    Awaad, Amani S.
    Moses, John E.
    [J]. JOURNAL OF SAUDI CHEMICAL SOCIETY, 2011, 15 (04) : 293 - 307
  • [2] Angelino D., 2017, FOOD FUNCT, V22, P1
  • [3] [Anonymous], 2003, REV MEX FITOPATOL
  • [4] What is oxidative stress?
    Betteridge, DJ
    [J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 2000, 49 (02): : 3 - 8
  • [5] OXIDATIVE STRESS: AN ESSENTIAL FACTOR IN THE PATHOGENESIS OF GASTROINTESTINAL MUCOSAL DISEASES
    Bhattacharyya, Asima
    Chattopadhyay, Ranajoy
    Mitra, Sankar
    Crowe, Sheila E.
    [J]. PHYSIOLOGICAL REVIEWS, 2014, 94 (02) : 329 - 354
  • [6] The antioxidant potential of the Mediterranean diet in patients at high cardiovascular risk: an in-depth review of the PREDIMED
    Billingsley, Hayley E.
    Carbone, Salvatore
    [J]. NUTRITION & DIABETES, 2018, 8
  • [7] Oxidative Stress and Antioxidant Defense
    Birben, Esra
    Sahiner, Umit Murat
    Sackesen, Cansin
    Erzurum, Serpil
    Kalayci, Omer
    [J]. WORLD ALLERGY ORGANIZATION JOURNAL, 2012, 5 : 9 - 19
  • [8] Dietary factors affecting polyphenol bioavailability
    Bohn, Torsten
    [J]. NUTRITION REVIEWS, 2014, 72 (07) : 429 - 452
  • [9] Molecular Approaches to Genetically Improve the Accumulation of Health-Promoting Secondary Metabolites in Staple CropsA Case Study: The Lipoxygenase-B1 Genes and Regulation of the Carotenoid Content in Pasta Products
    Borrelli, Grazia M.
    Trono, Daniela
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (07)
  • [10] Production of plant secondary metabolites: a historical perspective
    Bourgaud, F
    Gravot, A
    Milesi, S
    Gontier, E
    [J]. PLANT SCIENCE, 2001, 161 (05) : 839 - 851