Synthesis of fluorinated heterocycles

被引：171

作者：

Sloop, JC

Bumgardner, CL

Loehle, WD

机构：

[1] N Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA

[2] US Mil Acad, Dept Chem, W Point, NY 10996 USA

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2002年 / 118卷 / 1-2期

关键词：

fluorination; pyrazole; isoxazole; pyrimidine; quinoline;

D O I：

10.1016/S0022-1139(02)00221-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Selected 1,3-diketones having a trifluoromethyl group and/or a fluorine in the 2-position were condensed with aromatic hydrazines, hydroxylamine, urea, thiourea, guanidine, and substituted anilines producing pyrazoles, isoxazoles, pyrimidines, and quinolines, respectively, in yields ranging from 27 to 87%. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：135 / 147

页数：13

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