Synthesis of fluorinated heterocycles

被引：171
作者：
Sloop, JC
Bumgardner, CL
Loehle, WD
机构：
[1] N Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA
[2] US Mil Acad, Dept Chem, W Point, NY 10996 USA
来源：
JOURNAL OF FLUORINE CHEMISTRY | 2002年 / 118卷 / 1-2期
关键词：
fluorination; pyrazole; isoxazole; pyrimidine; quinoline;
D O I：
10.1016/S0022-1139(02)00221-X
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Selected 1,3-diketones having a trifluoromethyl group and/or a fluorine in the 2-position were condensed with aromatic hydrazines, hydroxylamine, urea, thiourea, guanidine, and substituted anilines producing pyrazoles, isoxazoles, pyrimidines, and quinolines, respectively, in yields ranging from 27 to 87%. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：135 / 147
页数：13
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