Cytokine regulation of endothelial cell function: From molecular level to the bedside

被引：320

作者：

Mantovani, A

Bussolino, F

Introna, M

机构：

[1] UNIV BRESCIA,DEPT BIOTECHNOL,SECT GEN PATHOL,I-25123 BRESCIA,ITALY

[2] UNIV TURIN,DIPARTIMENTO GENET BIOL & CHIM MED,I-10126 TURIN,ITALY

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 05期

关键词：

D O I：

10.1016/S0167-5699(97)81662-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Endothelial cells (ECs) participate in inflammatory and immune reactions by producing and responding to cytokines. The molecular basis underlying the functional reprogramming of endothelium is now being unraveled with the benefit of new data. Here, Alberto Mantovani and colleagues argue that activation of ECs provides a paradigm for the interpretation of the pathogenesis of diverse human diseases.

引用

页码：231 / 240

页数：10

共 116 条

[1] CELL-TYPE-SPECIFIC TRANSACTIVATION OF THE VCAM-1 PROMOTER THROUGH AN NF-KAPPA-B ENHANCER MOTIF [J].

AHMAD, M ;

MARUI, N ;

ALEXANDER, RW ;

MEDFORD, RM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (15) :8976-8983

[2]

ALMEIDA GD, 1994, BLOOD, V83, P370

[3] HUMAN INTERFERON-INDUCIBLE PROTEIN-10 IS A POTENT INHIBITOR OF ANGIOGENESIS IN-VIVO [J].

ANGIOLILLO, AL ;

SGADARI, C ;

TAUB, DD ;

LIAO, F ;

FARBER, JM ;

MAHESHWARI, S ;

KLEINMAN, HK ;

REAMAN, GH ;

TOSATO, G .

JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 182 (01) :155-162

[4] ENDOTHELIAL-CELL ACTIVATION AND THROMBOREGULATION DURING XENOGRAFT REJECTION [J].

BACH, FH ;

ROBSON, SC ;

FERRAN, C ;

WINKLER, H ;

MILLAN, MT ;

STUHLMEIER, KM ;

VANHOVE, B ;

BLAKELY, ML ;

VANDERWERF, WJ ;

HOFER, E ;

DEMARTIN, R ;

HANCOCK, WW .

IMMUNOLOGICAL REVIEWS, 1994, 141 :5-30

[5] INDUCTION OF NO SYNTHASE IN RAT CARDIAC MICROVASCULAR ENDOTHELIAL-CELLS BY IL-1-BETA AND IFN-GAMMA [J].

BALLIGAND, JL ;

UNGUREANULONGROIS, D ;

SIMMONS, WW ;

KOBZIK, L ;

LOWENSTEIN, CJ ;

LAMAS, S ;

KELLY, RA ;

SMITH, TW ;

MICHEL, T .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1995, 268 (03) :H1293-H1303

[6]

BAZAN JF, IN PRESS NATURE

[7] Identification of signal-induced I kappa B-alpha kinases in human endothelial cells [J].

Bennett, BL ;

Lacson, RG ;

Chen, CC ;

Cruz, R ;

Wheeler, JS ;

Kletzien, RF ;

Tomasselli, AG ;

Heinrikson, RL ;

Manning, AM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (33) :19680-19688

[8] Selective elevation of monocyte chemotactic protein-1 in the cerebrospinal fluid of AIDS patients with cytomegalovirus encephalitis [J].

Bernasconi, S ;

Cinque, P ;

Peri, G ;

Sozzani, S ;

Crociati, A ;

Torri, W ;

Vicenzi, E ;

Vago, L ;

Lazzarin, A ;

Poli, G ;

Mantovani, A .

JOURNAL OF INFECTIOUS DISEASES, 1996, 174 (05) :1098-1101

[9] MECHANISM OF THE TUMOR-NECROSIS-FACTOR ALPHA-MEDIATED INDUCTION OF ENDOTHELIAL TISSUE FACTOR [J].

BIERHAUS, A ;

ZHANG, YM ;

DENG, YH ;

MACKMAN, N ;

QUEHENBERGER, P ;

HAASE, M ;

LUTHER, T ;

MULLER, M ;

BOHRER, H ;

GRETEN, J ;

MARTIN, E ;

BAEUERLE, PA ;

WALDHERR, R ;

KISIEL, W ;

ZIEGLER, R ;

STERN, DM ;

NAWROTH, PP .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (44) :26419-26432

[10]

BRADLEY JR, 1995, AM J PATHOL, V146, P27

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