A highly selective turn-on chemosensor for Zn2+ in aqueous media and living cells

被引：34

作者：

Jung, Jae Min ^{[1
,2
]}

Lee, Seong Youl ^{[1
,2
]}

Nam, Eunju ^{[3
]}

Lim, Mi Hee ^{[3
]}

Kim, Cheal ^{[1
,2
]}

机构：

[1] Seoul Nat Univ Sci & Technol, Dept Fine Chem, Seoul 139743, South Korea

[2] Seoul Nat Univ Sci & Technol, Dept Interdisciplinary Bio IT Mat, Seoul 139743, South Korea

[3] Ulsan Natl Inst Sci & Technol, Dept Chem, Ulsan 44919, South Korea

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2017年 / 244卷

基金：

新加坡国家研究基金会;

关键词：

Fluorescent chemosensor; Zinc ion; Cell imaging; Test kit; Theoretical calculations; EFFECTIVE CORE POTENTIALS; FLUORESCENCE SENSOR; MOLECULAR CALCULATIONS; NANOMOLAR DETECTION; MONITORING ZN2+; ZINC; IONS; PROBE; WATER; CADMIUM;

D O I：

10.1016/j.snb.2017.01.076

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A new simple quinoline-based chemosensor 1 was synthesized for Zn2+. 1 showed the selective fluorescence enhancement in the presence of Zn2+ with a 1:1 stoichiometry in a near-perfect aqueous solution (bis-tris buffer:DMSO= 999:1), which was reversible with the addition of ethylenediaminetetraacetic acid (EDTA). The detection limit (0.6 M) of 1 for Zn2+ was much lower than World Health Organization guideline (76 p,mu M) in drinking water. 1 was successfully applied to quantify and image Zn2+ in water samples, test kit and living cells. The sensing mechanism of Zn2+ by 1 via the intramolecular charge transfer was explained by theoretical calculations. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：1045 / 1053

页数：9

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