Using the Antenna Effect as a Spectroscopic Tool: Photophysics and Solution Thermodynamics of the Model Luminescent Hydroxypyridonate Complex [EuIII(3,4,3-LI(1,2-HOPO))]-

被引：64

作者：

Abergel, Rebecca J. ^{[1
]}

D'Aleo, Anthony ^{[1
]}

Leung, Clara Ng Pak ^{[1
]}

Shuh, David K. ^{[1
]}

Raymond, Kenneth N. ^{[1
,2
]}

机构：

[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Chem Sci, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

INORGANIC CHEMISTRY | 2009年 / 48卷 / 23期

基金：

美国国家卫生研究院;

关键词：

LANTHANIDE COMPLEXES; STABILITY; EU(III); LIGANDS; AGENTS;

D O I：

10.1021/ic9013703

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Although widely used in bioassays, the spectrofluorimetric method described here uses the antenna effect as a tool to probe the thermodynamic parameters of ligands that sensitize lanthanide luminescence. The Eu3+ coordination chemistry, solution thermodynamic stability, and photophysical properties of the spermine-based hydroxypyridonate octadentate chelator 3,4,3-LI(1,2-HOPO) are reported. The complex [Eu-III(3,4,3-LI(1,2-HOPO))](-) luminesces with a long lifetime (805 mu s) and a quantum yield of 7.0% in aqueous solution, at pH 7.4. These remarkable optical properties were exploited to determine the high (and proton-independent) stability of the complex (log beta(110) = 20.2(2)) and to define the influence of the ligand scaffold on the stability and photophysical properties.

引用

页码：10868 / 10870

页数：3

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