Application of magnetic Fe3O4 nanoparticles as a reusable heterogeneous catalyst in the synthesis of β-lactams containing amino groups

被引:22
作者
Moslehi, Aleme [1 ]
Zarei, Maaroof [1 ]
机构
[1] Univ Hormozgan, Fac Sci, Dept Chem, Bandar Abbas 71961, Iran
关键词
STEREOSELECTIVE-SYNTHESIS; CHEMOSELECTIVE REDUCTION; BIOLOGICAL EVALUATION; NITRO-COMPOUNDS; 2-AZETIDINONES; HYDROGENATION; NITROARENES; EFFICIENT; DESIGN; IMINES;
D O I
10.1039/c9nj02759a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Herein we report the catalytic activity of magnetic Fe3O4 nanoparticles to promote the reduction of beta-lactams containing nitroaryl groups to beta-lactams containing aminoaryl groups in ethanol. The catalytic experimental conditions have been optimized to maximize the reaction productivity. This convenient and green catalytic methodology is effective to synthesize aminoaryl-beta-lactams containing sustainable groups such as Cl, MeO, alkenyl C?C, pyridine rings and beta-lactam carbonyl.
引用
收藏
页码:12690 / 12697
页数:8
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