Reusable Pd@PEG Catalyst for Aerobic Dehydrogenative C-H/C-H Arylations of 1,2,3-Triazoles

被引：19

作者：

Ferlin, Francesco ^{[1
,2
]}

Yetra, Santhivardhana Reddy ^{[1
]}

Warratz, Svenja ^{[1
]}

Vaccaro, Luigi ^{[2
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Georg August Univ Gottingen, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany

[2] Univ Perugia, Dipartimento Chim Biol & Biotecnol, Lab Green SOC, Via Elce di Sotto 8, I-06123 Perugia, Italy

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2019年 / 25卷 / 49期

关键词：

arylation; C-H activation; oxidation; palladium; polyethylene glycol; CROSS-COUPLING REACTIONS; IN-SITU GENERATION; IONIC LIQUIDS; PALLADIUM NANOPARTICLES; POLY(ETHYLENE GLYCOL); BIOLOGICAL EVALUATION; ORGANIC-SYNTHESIS; DIRECTING GROUPS; ACTIVATION; SYSTEM;

D O I：

10.1002/chem.201902901

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dehydrogenative C-H arylations of 1,2,3-triazoles were accomplished with the aid of a reusable palladium catalyst in PEG. The widely applicable oxidative palladium catalysis enabled the synthesis of fully decorated 1,2,3-triazoles with a broad functional-group tolerance and ample substrate scope. The sustainability of the aerobic C-H arylation was reflected by the use of PEG as green reaction medium and demonstrated by recycling studies of the catalyst and the reaction medium.

引用

页码：11427 / 11431

页数：5

共 69 条

[1] Cobalt-Catalyzed C-H Arylations, Benzylations, and Alkylations with Organic Electrophiles and Beyond [J].