On the Prins reaction of terminal olefins and formaldehyde in trifluoroacetic acid

被引：4
作者：
Almohseni, Hasanain A. A. [1 ]
Stent, Matthew A. H. [1 ]
Hodgson, David M. [1 ]
机构：
[1] Univ Oxford, Dept Chem, Chem Res Lab, Mansfield Rd, Oxford OX1 3TA, England
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2018年 / 54卷 / 04期
基金：
英国工程与自然科学研究理事会;
关键词：
formaldehyde; terminal alkenes; tetrahydropyrans; trifluoroacetic acid; Prins reaction; ALPHA-OLEFINS; HYDROGEN HALIDES; CONDENSATION; CYCLIZATION;
D O I：
10.1007/s10593-018-2293-z
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Prins reaction of 1-heptene, as a representative terminal alkene, with formaldehyde in trifluoroacetic acid produces 3-butyl-4-(trifluoroacetoxy)tetrahydropyran and/or 3-butyl-4-hydroxytetrahydropyran; it does not provide (as previously reported by Talipov and coworkers) a route to 3-alkyl-2,5-dihydrofurans and 4-alkyl-3-hydroxytetrahydrofurans.
引用
收藏
页码：474 / 477
页数：4
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