Efficient conjugate addition of 1H-indoles to electron-deficient olefins catalyzed by silica-supported sodium hydrogen sulfate (NaHSO4•SiO2)

被引：19
|
作者：
Das, Biswanath [1 ]
Chowdhury, Nikhil [1 ]
Damodar, K. [1 ]
Reddy, K. Ravinder [1 ]
机构：
[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India
来源：
HELVETICA CHIMICA ACTA | 2007年 / 90卷 / 02期
关键词：
D O I：
10.1002/hlca.200790040
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple, mild, rapid, and highly efficient method for the conjugate addition of 1H-indoles to electron-deficient olefins has been developed using NaHSO4 - SiO2 as heterogeneous catalyst. The conversion proceeds at room temperature, and the corresponding Michael adducts are formed in good-to-excellent yields.
引用
收藏
页码：340 / 345
页数：6
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