Test-retest study of fMRI signal change evoked by electroacupuncture stimulation

被引：105
作者：
Kong, Jian
Gollub, Randy L.
Webb, J. Megan
Kong, Jiang-Ti
Vangel, Mark G.
Kwong, Kenneth
机构：
[1] Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, MIT, HMS, Athnioula A Martinos Ctr Biomed Imaging, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, MIT, GCRC Biomed Imaging Core, Charlestown, MA USA
[4] Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA
来源：
NEUROIMAGE | 2007年 / 34卷 / 03期
关键词：
fMRI; brain imaging electroacupuncture; acupuncture; test-retest reproducibility; reliability; vision-related point;
D O I：
10.1016/j.neuroimage.2006.10.019
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Recent efforts to use fMRI to investigate the effects of acupuncture needle manipulation on the brain have yielded discrepant results. This study was designed to test the reliability of fMRI signal changes evoked by acupuncture stimulation. Six subjects participated in six identical scanning sessions consisting of four functional scans, one for each of the four conditions: electroacupuncture stimulation (2 Hz) at GB 37, UB 60, non-acupoint (NP), and a control task of the finger tapping. In the group analysis across all subjects and sessions, both the average ratings on a Subjective Acupuncture Sensation Scale and the average fMRI signal changes (increases and decreases) were similar for GB37, UB 60, and NP. Visual inspection of the activation maps from individual sessions and ICC analysis revealed that fMRI signal changes evoked by electroacupuncture stimulation were significantly more variable than those from the control finger-tapping task. The relatively large variability across different sessions within the same subject suggests multiple sessions should be used to accurately capture the activation patterns evoked by acupuncture stimulation at a particular point for a specific subject. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码：1171 / 1181
页数：11
相关论文
共 57 条
[1]   Long-term test-retest reliability of functional MRI in a classification learning task [J].
Aron, AR ;
Gluck, MA ;
Poldrack, RA .
NEUROIMAGE, 2006, 29 (03) :1000-1006
[2]   Reproducibility of fMRI results across four institutions using a spatial working memory task [J].
Casey, BJ ;
Cohen, JD ;
O'Craven, K ;
Davidson, RJ ;
Irwin, W ;
Nelson, CA ;
Noll, DC ;
Hu, XP ;
Lowe, MJ ;
Rosen, BR ;
Truwitt, CL ;
Turski, P .
NEUROIMAGE, 1998, 8 (03) :249-261
[3]  
Cheng X, 1987, Chinese Acupuncture and Moxibustion
[4]   RETRACTED: New findings of the correlation between acupoints and corresponding brain cortices using functional MRI (Retracted Article. See vol 103, pg 10527, 2006) [J].
Cho, ZH ;
Chung, SC ;
Jones, JP ;
Park, JB ;
Park, HJ ;
Lee, HJ ;
Wong, EK ;
Min, BI .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (05) :2670-2673
[5]   Functional MRI in healthy subjects during acupuncture: different effects of needle rotation in real and false acupoints [J].
Fang, JL ;
Krings, T ;
Weidemann, J ;
Meister, IG ;
Thron, A .
NEURORADIOLOGY, 2004, 46 (05) :359-362
[6]  
Fleiss J., 1986, Reliability of measurement: the design and analysis of clinical experiments
[7]   CHARACTERIZING EVOKED HEMODYNAMICS WITH FMRI [J].
FRISTON, KJ ;
FRITH, CD ;
TURNER, R ;
FRACKOWIAK, RSJ .
NEUROIMAGE, 1995, 2 (02) :157-165
[8]   Multisubject fMRI studies and conjunction analyses [J].
Friston, KJ ;
Holmes, AP ;
Price, CJ ;
Büchel, C ;
Worsley, KJ .
NEUROIMAGE, 1999, 10 (04) :385-396
[9]   ANALYSIS OF FMRI TIME-SERIES REVISITED [J].
FRISTON, KJ ;
HOLMES, AP ;
POLINE, JB ;
GRASBY, PJ ;
WILLIAMS, SCR ;
FRACKOWIAK, RSJ ;
TURNER, R .
NEUROIMAGE, 1995, 2 (01) :45-53
[10]   Is there a BOLD response of the visual cortex on stimulation of the vision-related Acupoint GB 37? [J].
Gareus, IK ;
Lacour, M ;
Schulte, AC ;
Hennig, J .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2002, 15 (03) :227-232
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