Non-covalent surface interactions between silicone and biological macromolecules yield bioreactive substances

被引：0
作者：
Kossovsky, N
机构：
[1] Biomaterials Bioreactivity C., Dept. of Pathol. and Lab. Medicine, University of California-Los Angeles, Los Angeles
来源：
APPLIED ORGANOMETALLIC CHEMISTRY | 1997年 / 11卷 / 05期
关键词：
adsorption; disease; environmental chemistry; non-covalent surface interactions; pathology; silicone; toxicity;
D O I：
10.1002/(SICI)1099-0739(199705)11:5<353::AID-AOC595>3.0.CO;2-5
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
While most organometallics enter the environment through their industrial release, silicones are organometallic compounds purposefully introduced in high volume directly into healthy humans. A chemically centered study of the behavior of silicones in the biological environment reveals numerous degradative reactions and surface interactions that can produce bioreactive substances. Data from a variety of disciplines suggest that the preponderance of evidence supports the argument that silicone is a toxic organometallic. (C) 1997 by John Wiley & Sons, Ltd.
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页码：353 / 368
页数：16
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