Wound therapy with autologous bone marrow stem cells in diabetic patients with ischaemia-induced tissue ulcers affecting the lower limbs

被引:42
作者
Kirana, S.
Stratmann, B.
Lammers, D.
Negrean, M.
Stirban, A.
Minartz, P.
Koerperich, H.
Gastens, M. H.
Goetting, C.
Prohaska, W.
Kleesiek, K.
Tschoepe, D.
机构
[1] Ruhr Univ Bochum, Ctr Diabet, Heart & Diabet Ctr NRW, D-4630 Bochum, Germany
[2] Ruhr Univ Bochum, Inst Radiol Nucl Med & Mol Imaging, Heart & Diabet Ctr NRW, D-4630 Bochum, Germany
关键词
D O I
10.1111/j.1742-1241.2007.01303.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Previous studies suggest that autologous transplantation of bone marrow mononuclear cells is safe and effective in inducing therapeutic angiogenesis in patients with peripheral arterial occlusive disease (PAOD). Here we discuss a multidisciplinary approach to treating PAOD with a focus on the use of angiological diagnostic tools. We conclude that our autologous stem cell therapy is working in this patient and it is a potential new therapeutic option for diabetic patients with chronic foot ulcers induced by critical limb ischaemia.
引用
收藏
页码:690 / 692
页数:3
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