Resonance Rayleigh scattering method for the determination of raloxifene with Evans blue

被引：0

作者：

Fan, L ^{[1
]}

Liu, SP ^{[1
]}

Yang, DC ^{[1
]}

Hu, XL ^{[1
]}

机构：

[1] SW China Normal Univ, Inst Environm Chem, Chongqing 400715, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2002年 / 20卷 / 12期

关键词：

resonance Rayleigh scattering; raloxifene; Evans blue; ion-association complex;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The intensity of resonance Rayleigh scattering (RRS) of Evans blue (EB) or raloxifene hydrochloride (Ralo) is very weak, but it can be enhanced significantly and a new RRS spectrum appears when both of them interact to form an ion-association complex in sodium acetate-hydrochloric acid buffer solution at pH 1.8. The intensity of RRS is directly proportional to the concentration of Ralo in the range of 0-8.3 mug (.) mL(-1), and the detection limit for Ralo (sigma = 3) is 18.9 ng (.) mL(-1). The method has high sensitivity and fairly good selectivity. Based on the above evidences, a new facile method for the determination of trace amount of Ralo has been established with satisfactory results.

引用

页码：1552 / 1556

页数：5

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