Synthesis and in vitro antibacterial activity of 3-[N-methyl-N-(3-methyl-1,3-thiazolium-2-yl)amino]methyl cephalosporin derivatives

被引：18
|
作者：
Kim, SH
Son, H
Nam, G
Chi, DY
Kim, JH
机构：
[1] Korea Inst Sci & Technol, Biochem Res Ctr, Seoul, South Korea
[2] Inha Univ, Dept Chem, Inchon 402751, South Korea
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2000年 / 10卷 / 11期
关键词：
D O I：
10.1016/S0960-894X(00)00130-X
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The new cephalosporins having N-linked quarternary ammonium salt at C-3 position were prepared from the reaction of 2-methylimino-3-methyl-1,3-thiazoline derivatives with cephalosporins. Also antimicrobial activities of those compounds were determined. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1143 / 1145
页数：3
相关论文
共 50 条
  • [1] N-methyl-N-(2-nitrophenyl)nitramine and N-methyl-N-(3-nitrophenyl)nitramine
    Zarychta, B
    Piecyk-Mizgata, A
    Daszkiewicz, Z
    Zaleski, J
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2005, 61 : O515 - O517
  • [2] Acetylcholinesterase inhibitors:: Synthesis and structure-activity relationships of ω-[N-methyl-N-(3-alkylcarbamoyloxyphenyl)methyl] aminoalkoxyheteroaryl derivatives
    Rampa, A
    Bisi, A
    Valenti, P
    Recanati, M
    Cavalli, A
    Andrisano, V
    Cavrini, V
    Fin, L
    Universi, GDOS
    Buriani, A
    Giusti, P
    JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (21) : 3976 - 3986
  • [3] 1-[N-Methyl-N-(Phenyl)amino]-3-(4-Methylphenyl)Thiourea
    Yeo, Chien Ing
    Tiekink, Edward R. T.
    MOLBANK, 2019, (01)
  • [4] Rapid synthesis of N-methyl-N-(3-nitrobenzyl)formamide
    Rodgers, Megan
    Bobyleva, Lioudmila
    Bobylev, Mikhail
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
  • [5] Rapid synthesis of N-methyl-N-(3-trifluoromethylbenzyl)formamide
    Dostert-Azzarello, Tiffany
    Bobyleva, Lioudmila
    Bobylev, Mikhail
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [6] Acetylcholinesterase inhibitors:: SAR and kinetic studies on ω-[N-methyl-N-(3-alkylcarbamoyloxyphenyl)methyl]aminoalkoxyaryl derivatives
    Rampa, A
    Piazzi, L
    Belluti, F
    Gobbi, S
    Bisi, A
    Bartolini, M
    Andrisano, V
    Cavrini, V
    Cavalli, A
    Recanatini, M
    Valenti, P
    JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (23) : 3810 - 3820
  • [7] 3-(1,3-Benzodioxol-5-yl)-3-hydroxy-N-methyl-N-phenylpropionamide
    Yu, Zhi-Fang
    Li, Juan
    Zhao, Zhi-Min
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O5614 - O5615
  • [8] Synthesis of Diethyl N-{4-[N-Methyl-N-(3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)amino-2-hydroxypropyl)amino]-benzoyl}-L-glutamate and Its Derivatives
    Deng, Xiling
    Liu, Weidong
    Li, Chao
    Zhang, Zhili
    Wang, Xiaowei
    Liu, Junyi
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2011, 31 (01) : 75 - 81
  • [9] Synthesis, crystal, computational study and in vitro anti-tuberculosis activity of N-(furan-2-yl-methyl)-N-(phenyl(quinolin-3-yl)methyl) acetamide derivatives
    Bai, Yuefei
    Wang, Lijuan
    Chen, Yu
    Yuan, Lei
    Xu, Wei
    Sun, Tiemin
    JOURNAL OF MOLECULAR STRUCTURE, 2011, 1005 (1-3) : 113 - 120
  • [10] SYNTHESIS OF 2-METHYL-5-NITRO-N-(4-(3-((3-PHENYLQUINOXALIN-2-YL) METHYL) PHENOXY) PHENYL) BENZENESULFONAMIDE AND THEIR ANTIMICROBIAL ACTIVITY
    Patel, Rajarshi N.
    Vyas, K. B.
    Patel, Piysh V.
    Patel, Dinesh S.
    HETEROCYCLIC LETTERS, 2013, 3 (03): : 341 - 347
12345