THE EFFECT OF FUNCTIONAL LIMITATIONS AND FATIGUE ON THE QUALITY OF LIFE IN PEOPLE WITH MULTIPLE SCLEROSIS

被引：25

作者：

Calazans Nogueira, Leandro Alberto ^{[2
,4
]}

Nobrega, Felipe Resende ^{[3
]}

Lopes, Katia Nogueira

Santos Thuler, Luiz Claudio ^{[5
]}

Papais Alvarenga, Regina Maria ^{[1
]}

机构：

[1] UNIRIO, Dept Neurol, Neurol Grad Program, Rio De Janeiro, Brazil

[2] Univ Gama Filho, Phys Therapy Dept, Rio De Janeiro, Brazil

[3] Celso Lisboa Univ, Phys Therapy Dept, Rio De Janeiro, Brazil

[4] Hosp Univ Gaffree & Guinle, Dept Neurol, BR-20270004 Rio De Janeiro, Brazil

[5] UNIRIO, Neurol Grad Program, Rio De Janeiro, Brazil

来源：

ARQUIVOS DE NEURO-PSIQUIATRIA | 2009年 / 67卷 / 3B期

关键词：

multiple sclerosis; quality of life; physically disable; gait; DIAGNOSTIC-CRITERIA; DEPRESSION; DISABILITY; IMPACT; POPULATION; GUIDELINES; SCALE;

D O I：

10.1590/S0004-282X2009000500006

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The purpose of this study was to determine the effect of functional limitations and fatigue on the quality of life (QoL) in people with multiple sclerosis (MS). A descriptive case series study at Lagoa Hospital Rio de Janeiro, Brazil was carried. The main outcome measurements were demographic variables, QoL (SF-36 v.1), disability (EDSS), motor function of the upper limb (Box & Blocks test), Tone (Modified Ashworth Scale), gait (Hauser ambulatory index) and fatigue (Fatigue Severity Scale). Sixty one patients fulfilled the study criteria. The mean age of patients was 39 years and 74% of patients were female. The most of cases presented mild disability (EDSS <= 3.5). A decrease was found in all domains of QoL. It was found association between physical functioning and the variables of EDSS, fatigue, lower limb tone and gait. Gait, disability, hypertonia of the lower limbs and fatigue negatively affected QoL in people with MS.

引用

页码：812 / 817

页数：6

共 30 条

[1]

ALVARENGA RMP, 2002, MIRADA IBERO AM, P129

[2] Health-related quality of life and its relationship to cognitive and emotional functioning in multiple sclerosis patients [J].

Benito-León, J ;

Morales, JM ;

Rivera-Navarro, J .

EUROPEAN JOURNAL OF NEUROLOGY, 2002, 9 (05) :497-502

[3] INTERRATER RELIABILITY OF A MODIFIED ASHWORTH SCALE OF MUSCLE SPASTICITY [J].

BOHANNON, RW ;

SMITH, MB .

PHYSICAL THERAPY, 1987, 67 (02) :206-207

[4]

Ciconelli RM., 1999, REV BRAS REUMATOL, V39, P143

[5] A study of the quality of life in cases of multiple sclerosis [J].

Delgado-Mendilívar, JM ;

Cadenas-Díaz, JC ;

Fernández-Torrico, JM ;

Navarro-Mascarell, G ;

Izquierdo, G .

REVISTA DE NEUROLOGIA, 2005, 41 (05) :257-262

[6] Epidemiology of 118 cases of multiple sclerosis after 15 years of follow-up on the reference center of Hospital da Restauracao, Recife, Pernambuco, Brazil [J].

Ferreira, MLB ;

Machado, MIM ;

Vilela, ML ;

Guedes, MJ ;

Ataide, L ;

Santos, S ;

Laurentino, SG .

ARQUIVOS DE NEURO-PSIQUIATRIA, 2004, 62 (04) :1027-1032

[7] Health problems and health-related quality of life in people with multiple sclerosis [J].

Forbes, A ;

While, A ;

Mathes, L ;

Griffiths, P .

CLINICAL REHABILITATION, 2006, 20 (01) :67-78

[8] Depression and quality of life in multiple sclerosis [J].

Fruehwald, S ;

Loeffler-Stastka, H ;

Eher, R ;

Saletu, B ;

Baumhackl, U .

ACTA NEUROLOGICA SCANDINAVICA, 2001, 104 (05) :257-261

[9] INTENSIVE IMMUNOSUPPRESSION IN PROGRESSIVE MULTIPLE-SCLEROSIS - A RANDOMIZED, 3-ARM STUDY OF HIGH-DOSE INTRAVENOUS CYCLOPHOSPHAMIDE, PLASMA-EXCHANGE, AND ACTH [J].

HAUSER, SL ;

DAWSON, DM ;

LEHRICH, JR ;

BEAL, MF ;

KEVY, SV ;

PROPPER, RD ;

MILLS, JA ;

WEINER, HL .

NEW ENGLAND JOURNAL OF MEDICINE, 1983, 308 (04) :173-180

[10] Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners [J].

Janssens, ACJW ;

Doorn, PA ;

Boer, JB ;

Meché, FGA ;

Passchier, J ;

Hintzen, RQ .

ACTA NEUROLOGICA SCANDINAVICA, 2003, 108 (06) :389-395

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