Copper-Catalyzed Hydroalkylation of Alkynes: Addition of sp3 C-H Bonds Across Carbon-Carbon Triple Bonds

被引：35

作者：

Huang, Lehao ^{[1
]}

Cheng, Kai ^{[1
]}

Yao, Bangben ^{[1
]}

Zhao, Jinlong ^{[1
]}

Zhang, Yuhong ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2009年 / 20期

关键词：

C-H activation; copper; addition reactions; alkynes; tert-butyl hydroperoxide; OXIDATIVE CYANATION; HYDROGEN-PEROXIDE; TERTIARY-AMINES; FUNCTIONALIZATION; ADJACENT; ARYLATION; ALKENYLATION; ACTIVATION; HYDROARYLATION; ALKYNYLATION;

D O I：

10.1055/s-0029-1216991

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regioselective copper-catalyzed addition of sp(3) C-H bonds adjacent to an oxygen atom to various alkynes has been accomplished under mild reactions conditions in the presence of tert-butyl hydroperoxide to give the corresponding alkenylated products.

引用

页码：3504 / 3510

页数：7

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