Aspirin for primary prevention: Is this the end of the road?

被引：11

作者：

Singal, Aayush Kumar ^{[1
]}

Karthikeyan, Ganesan ^{[1
]}

机构：

[1] AIIMS, Cardiothorac Sci Ctr, Dept Cardiol, 7th Floor, New Delhi, India

来源：

INDIAN HEART JOURNAL | 2019年 / 71卷 / 02期

关键词：

Aspirin; Primary prevention; MI-bleed trade-off; LOW-DOSE ASPIRIN; CARDIOVASCULAR EVENTS; DIABETES-MELLITUS; DISEASE; RISK; THERAPY;

D O I：

10.1016/j.ihj.2019.04.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aspirin is one of the oldest and most commonly used cardiovascular drugs. Despite there being high-quality evidence supporting the use of aspirin for patients with known cardiovascular disease, a definitive consensus regarding its use for patients at risk for cardiovascular disease (and without established cardiovascular disease) has never been reached. Many randomized control trials have produced conflicting results, and consequently, society guidelines have issued differring recommendations. Three major trials were published in 2018, which supplement the existing data on aspirin's role in primary prevention and provide further guidance on this contentious issue. This article reviews the history of aspirin through the last two decades, with special emphasis on these new trials. (C) 2019 Cardiological Society of India.

引用

页码：113 / 117

页数：5

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