2019 EACTS Expert Consensus on long-term mechanical circulatory support

被引:285
作者
Potapov, Evgenij V. [1 ,2 ]
Antonides, Christiaan [3 ]
Crespo-Leiro, Maria G. [4 ]
Combes, Alain [5 ,6 ]
Faerber, Gloria [7 ]
Hannan, Margaret M. [8 ]
Kukucka, Marian [9 ]
de Jonge, Nicolaas [10 ]
Loforte, Antonio [11 ]
Lund, Lars H. [12 ]
Mohacsi, Paul [13 ]
Morshuis, Michiel [14 ]
Netuka, Ivan [15 ]
Ozbaran, Mustafa [16 ]
Pappalardo, Federico [17 ]
Scandroglio, Anna Mara [18 ]
Schweiger, Martin [19 ]
Tsui, Steven [20 ]
Zimpfer, Daniel [21 ]
Gustafsson, Finn [22 ]
机构
[1] German Heart Ctr Berlin, Dept Cardiothorac & Vasc Surg, Berlin, Germany
[2] DZHK German Ctr Cardiovasc Res, Partner Site Berlin, Berlin, Germany
[3] Erasmus MC, Dept Cardiothorac Surg, Rotterdam, Netherlands
[4] UDC, CIBERCV, Complexo Hosp Univ A Coruna CHUAC, Inst Invest Biomed A Corua INIBIC, La Coruna, Spain
[5] Sorbonne Univ, INSERM, Inst Cardiometab & Nutr, Paris, France
[6] Hop La Pitie Salpetriere, APHP, Inst Cardiol, Serv Med Intens Reanimat, Paris, France
[7] Friedrich Schiller Univ Jena, Jena Univ Hosp, Dept Cardiothorac Surg, Jena, Germany
[8] Univ Coll Dublin, Dept Med Microbiol, Dublin, Ireland
[9] German Heart Ctr Berlin, Dept Anaesthesiol, Berlin, Germany
[10] Univ Med Ctr Utrecht, Dept Cardiol, Utrecht, Netherlands
[11] Univ Bologna, Transplantat & Vasc Surg, S Orsola Hosp, Dept Cardiothorac, Bologna, Italy
[12] Karolinska Univ Hosp, Heart & Vasc Theme, Karolinska Inst, Dept Med, Solna, Sweden
[13] Bern Univ Hosp, Inselspital, Swiss Cardiovasc Ctr, Dept Cardiovasc Surg, Bern, Switzerland
[14] Herz & Diabet Zentrum Nordrhein Westfalen, Clin Thorac & Cardiovasc Surg, Bad Oeynhausen, Germany
[15] Inst Clin & Expt Med IKEM, Prague, Czech Republic
[16] Ege Univ, Dept Cardiovasc Surg, Izmir, Turkey
[17] Univ Vita Salute San Raffaele, Hosp San Raffaele, Cardiac Intens Care, Adv Heart Failure & Mech Circulatory Support Prog, Milan, Italy
[18] Univ Vita Salute San Raffaele, Hosp San Raffaele, Dept Anesthesia & Intens Care, Milan, Italy
[19] Zurich Childrens Hosp, Dept Congenital Pediat Surg, Zurich, Switzerland
[20] Royal Papworth Hosp, Cambridge, England
[21] Med Univ Vienna, Div Cardiac Surg, Dept Surg, Vienna, Austria
[22] Rigshosp, Dept Cardiol, 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
关键词
Mechanical circulatory support; Left ventricular assist devices; Heart failure; Expert consensus; VENTRICULAR-ASSIST DEVICE; TOTAL ARTIFICIAL-HEART; INHALED NITRIC-OXIDE; EXTRACORPOREAL MEMBRANE-OXYGENATION; AORTIC-VALVE INSUFFICIENCY; PULMONARY-ARTERY CATHETER; IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS; LUNG TRANSPLANTATION GUIDELINES; PEDIATRIC INTERAGENCY REGISTRY; DRUG ADMINISTRATION-APPROVAL;
D O I
10.1093/ejcts/ezz098
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Long-term mechanical circulatory support (LT-MCS) is an important treatment modality for patients with severe heart failure. Different devices are available, and many-sometimes contradictory-observations regarding patient selection, surgical techniques, perioperative management and follow-up have been published. With the growing expertise in this field, the European Association for Cardio-Thoracic Surgery (EACTS) recognized a need for a structured multidisciplinary consensus about the approach to patients with LT-MCS. However, the evidence published so far is insufficient to allow for generation of meaningful guidelines complying with EACTS requirements. Instead, the EACTS presents an expert opinion in the LT-MCS field. This expert opinion addresses patient evaluation and preoperative optimization as well as management of cardiac and non-cardiac comorbidities. Further, extensive operative implantation techniques are summarized and evaluated by leading experts, depending on both patient characteristics and device selection. The faculty recognized that postoperative management is multidisciplinary and includes aspects of intensive care unit stay, rehabilitation, ambulatory care, myocardial recovery and end-of-life care and mirrored this fact in this paper. Additionally, the opinions of experts on diagnosis and management of adverse events including bleeding, cerebrovascular accidents and device malfunction are presented. In this expert consensus, the evidence for the complete management from patient selection to end-of-life care is carefully reviewed with the aim of guiding clinicians in optimizing management of patients considered for or supported by an LT-MCS device.
引用
收藏
页码:230 / 270
页数:41
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