Role of microglia in spinal cord injury

被引：80

作者：

Kroner, Antje ^{[1
,2
,3
]}

Almanza, Jose Rosas ^{[1
,2
,3
]}

机构：

[1] Med Coll Wisconsin, Dept Neurosurg, Milwaukee, WI 53226 USA

[2] Med Coll Wisconsin, Dept Microbiol & Immunol, Milwaukee, WI 53226 USA

[3] Clement J Zablocki Vet Affairs Med Ctr, Milwaukee, WI USA

来源：

NEUROSCIENCE LETTERS | 2019年 / 709卷

关键词：

Spinal cord injury; Microglia; Macrophage; Astrocyte; TOLL-LIKE RECEPTORS; PROMOTES RECOVERY; CNS; SYSTEM; BRAIN; CELL; MACROPHAGES; MONOCYTES; REVEALS; DAMAGE;

D O I：

10.1016/j.neulet.2019.134370

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Myeloid cells are important effector cells in the injured spinal cord tissue. Microglia and monocyte-derived macrophages serve important functions in the injured spinal cord, and their distinctive roles can now be studied more efficiently with the help of reporter mice and cell specific markers that were described in recent years. Focusing on microglia, this review discusses the microglial response to injury, microglia specific effects and the interaction between microglia and other cell types in the injured spinal cord.

引用

页数：5

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