Polypeptide growth factors: targeted delivery systems

被引:215
作者
Nimni, ME [1 ]
机构
[1] UNIV SO CALIF, CHILDRENS HOSP LOS ANGELES, SCH MED, DEPT MED & SURG, LOS ANGELES, CA 90027 USA
关键词
growth factors; targeted delivery; TGF-beta; BMPs;
D O I
10.1016/S0142-9612(97)00050-1
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Growth factors are becoming extremely valuable tools in our attempts to understand the mechanisms that modulate cellular activities. Their targeting to appropriate cells and maintaining adequate pharmacological levels becomes essential, particularly in view of the different effects that these compounds have on various cells and the dose dependence of their response. Within this context, this review focusses primarily on the delivery of growth factors involved in the processes of wound healing and tissue repair. (C) 1997 Elsevier Science Limited. All rights reserved.
引用
收藏
页码:1201 / 1225
页数:25
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