Marginal Regression Analysis for Semi-Competing Risks Data Under Dependent Censoring

被引:21
作者
Ding, A. Adam [1 ]
Shi, Guangkai [1 ]
Wang, Weijing [2 ]
Hsieh, Jin-Jian [3 ]
机构
[1] Northeastern Univ, Dept Math, Boston, MA 02115 USA
[2] Natl Chiao Tung Univ, Inst Stat, Hsinchu, Taiwan
[3] Natl Chung Cheng Univ, Dept Math, Taipei, Taiwan
关键词
artificial censoring; log-rank statistic; multiple events data; transformation model; MODEL; RESIDUALS; CHECKING;
D O I
10.1111/j.1467-9469.2008.00635.x
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Multiple events data are commonly seen in medical applications. There are two types of events, namely terminal and non-terminal. Statistical analysis for non-terminal events is complicated due to dependent censoring. Consequently, joint modelling and inference are often needed to avoid the problem of non-identifiability. This article considers regression analysis for multiple events data with major interest in a non-terminal event such as disease progression. We generalize the technique of artificial censoring, which is a popular way to handle dependent censoring, under flexible model assumptions on the two types of events. The proposed method is applied to analyse a data set of bone marrow transplantation.
引用
收藏
页码:481 / 500
页数:20
相关论文
共 19 条
[1]  
Andersen Per K, 2012, STAT MODELS BASED CO
[2]   A two-sample comparison for multiple ordered event data [J].
Chang, SH .
BIOMETRICS, 2000, 56 (01) :183-189
[3]   Adaptation of bivariate frailty models for prediction, with application to biological markers as prognostic indicators [J].
Day, R ;
Bryant, J .
BIOMETRIKA, 1997, 84 (01) :45-56
[4]  
Fine J P, 2001, Biostatistics, V2, P85, DOI 10.1093/biostatistics/2.1.85
[5]   A proportional hazards model for the subdistribution of a competing risk [J].
Fine, JP ;
Gray, RJ .
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1999, 94 (446) :496-509
[6]   On semi-competing risks data [J].
Fine, JP ;
Jiang, H ;
Chappell, R .
BIOMETRIKA, 2001, 88 (04) :907-919
[7]   Semiparametric analysis of recurrent events data in the presence of dependent censoring [J].
Ghosh, D ;
Lin, DY .
BIOMETRICS, 2003, 59 (04) :877-885
[8]   Rank-based inference for the accelerated failure time model [J].
Jin, ZZ ;
Lin, DY ;
Wei, LJ ;
Ying, ZL .
BIOMETRIKA, 2003, 90 (02) :341-353
[9]  
Kalbfleisch JD., 2002, The Statistical Analysis of Failure Time Data, V2
[10]  
Klein JP, 2003, Techniques for censored and truncated data, V2nd