Electrocatalytic Multicomponent Reaction for Synthesis of Nanoparticles of Spirooxindole Derivatives from Isatins, Malononitrile, and Dimedone

被引：22

作者：

Darvish, Zahra Mohammad ^{[1
]}

Mirza, Behrooz ^{[1
]}

Makarem, Somayeh ^{[2
]}

机构：

[1] Islamic Azad Univ, South Tehran Branch, Dept Chem, Tehran, Iran

[2] Islamic Azad Univ, Karaj Branch, Dept Chem, Karaj, Iran

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2017年 / 54卷 / 03期

关键词：

ELECTROORGANIC SYNTHESIS; SPIRO;

D O I：

10.1002/jhet.2755

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An electrocatalytic multicomponent synthesis of nanoparticles of spirooxindole is described, using an electrogenerated base of the anion of propanol in a one-pot, three component condensations of an isatins, dimedone, and malononitrile in an undivided cell in the presence of sodium bromide as an electrolyte at 50 degrees C.

引用

页码：1763 / 1766

页数：4

共 24 条

[1] Synthesis and evaluation of some new spiro indoline-based heterocycles as potentially active antimicrobial agents [J].

Abdel-Rahman, AH ;

Keshk, EM ;

Hanna, MA ;

El-Bady, SM .

BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (09) :2483-2488

[2]

Aditya K., 2001, PEDIAT DERMATOL, V18, P433

[3] Facile, Regio- and Diastereoselective Synthesis of Spiro-Pyrrolidine and Pyrrolizine Derivatives and Evaluation of Their Antiproliferative Activities [J].

Almansour, Abdulrahman I. ;

Kumar, Raju Suresh ;

Beevi, Farzana ;

Shirazi, Amir Nasrolahi ;

Osman, Hasnah ;

Ismail, Rusli ;

Choon, Tan Soo ;

Sullivan, Brian ;

McCaffrey, Kellen ;

Nahhas, Alaa ;

Parang, Keykavous ;

Ali, Mohamed Ashraf .

MOLECULES, 2014, 19 (07) :10033-10055

[4] Current and emerging targets to treat neuropathic pain [J].

Butera, John A. .

JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (11) :2543-2546

[5]

FLEISCHMANN M, 1969, PLATIN MET REV, V13, P46

[6] Organic electrosynthesis: a promising green methodology in organic chemistry [J].

Frontana-Uribe, Bernardo A. ;

Little, R. Daniel ;

Ibanez, Jorge G. ;

Palma, Agustin ;

Vasquez-Medrano, Ruben .

GREEN CHEMISTRY, 2010, 12 (12) :2099-2119

[7]

Hans S., 2006, Int. Pat., Patent No. 2006122769

[8]

Hans S., 2006, App. No, Patent No. [PCT/EP2006/004651, 2006004651]

[9] Synthesis of new spiroindolinones incorporating a benzothiazole moiety as antioxidant agents [J].

Karali, Nilguen ;

Guzel, Ozlen ;

Ozsoy, Nurten ;

Ozbey, Suheyla ;

Salman, Aydin .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (03) :1068-1077

[10] Synthesis and anticancer activity of novel spiro-isoxazoline and spiro-isoxazolidine derivatives of α-santonin [J].

Khazir, Jabeena ;

Singh, Parvinder Pal ;

Reddy, D. Mahendhar ;

Hyder, Irfan ;

Shafi, Syed ;

Sawant, S. D. ;

Chashoo, Gousia ;

Mahajan, Ajay ;

Alam, M. S. ;

Saxena, A. K. ;

Arvinda, S. ;

Gupta, B. D. ;

Kumar, H. M. Sampath .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 63 :279-289

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