Disruption of the HIV-1 protease dimer with interface peptides:: Structural studies using NMR spectroscopy combined with [2-13C]-Trp selective labeling

被引:25
作者
Frutos, Silvia
Rodriguez-Mias, Ricard A.
Madurga, Sergio
Collinet, Bruno
Reboud-Ravaux, Michele
Ludevid, Dolors
Giralt, Ernest
机构
[1] Inst Rec Biomed, E-08028 Barcelona, Spain
[2] Univ Barcelona, Dept Quim Fis, E-08028 Barcelona, Spain
[3] Univ Paris 06, CNRS, FRE2852, F-75251 Paris, France
关键词
HIV-1; protease; dimerization inhibitor; NMR; Trp selective labeling; peptide;
D O I
10.1002/bip.20685
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:164 / 173
页数:10
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