Hydrogel-Based Materials for Delivery of Herbal Medicines

被引:85
作者
Lai, Wing-Fu [1 ,2 ]
Rogach, Andrey L. [3 ,4 ]
机构
[1] Shenzhen Univ, Dept Pharm, Hlth Sci Ctr, Shenzhen 518060, Peoples R China
[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China
[3] City Univ Hong Kong, Dept Phys & Mat Sci, Hong Kong, Hong Kong, Peoples R China
[4] City Univ Hong Kong, Ctr Funct Photon, Hong Kong, Hong Kong, Peoples R China
关键词
hydrogels; oriental medicine; drug delivery; herb; sustained release; TRADITIONAL CHINESE MEDICINE; IN-VIVO ASSESSMENT; DRUG-DELIVERY; ALGINATE NANOPARTICLES; HOUTTUYNIA-CORDATA; PEG HYDROGEL; RELEASE; EXTRACT; CURCUMIN; CHITOSAN;
D O I
10.1021/acsami.6b16120
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Herbal medicine, as an integral component of oriental medicine, has assimilated into the lives of Asian people for millennia. The therapeutic efficiency of herbal extracts and ingredients has, however, been limited by various factors, including the lack of targeting capacity and poor bioavailability. Hydrogels are hydrophilic polymer networks that can imbibe a substantial amount of fluids. They are biocompatible, and may enable sustained drug release. Hydrogels, therefore, have attracted widespread studies in pharmaceutical formulation. This article first reviews the latest progress in the development of hydrogel-based materials as carriers of herbal medicines, followed by a discussion of the relationships between hydrogel properties and carrier performance. Finally, the promising potential of using hydrogels to combine medicinal herbs with synthetic drugs in one single treatment will be highlighted as an avenue for future research.
引用
收藏
页码:11309 / 11320
页数:13
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