Solitary plasmacytoma of the sphenoid. A case report

A rare case of sphenoidal plasmacytoma in a 79 year-old male patient is reported. The diagnosis was preoperatively considered because of associated dysprotememia and it was histopathologically confirmed on a transphenoidal biopsy specimen. Initial evaluation disclosed no systemic dissemination of the disease and a solitary plasmacytoma was diagnosed. Radiotherapy was delivered with subsequent clinical improvement and significant tumor reduction was illustrated on follow-up imaging studies. Twenty-two months after diagnosis, the patient remains asymptomatic without evidence of transformation to multiple myeloma. Only 7 comparable cases have been reported in the literature. The diagnostic, pathological and nosographic features of sphenoid plasmacytomas are discussed.