Absolute configuration of (+)-pinoresinol 4-O-[6"-O-galloyl]-β-D-glucopyranoside, macarangiosides E, and F isolated from the leaves of Macaranga tanarius

被引：25

作者：

Matsunami, Katsuyoshi ^{[1
]}

Otsuka, Hideaki ^{[1
]}

Kondo, Kazunari ^{[2
]}

Shinzato, Takakazu ^{[3
]}

Kawahata, Masatoshi ^{[4
]}

Yamaguchi, Kentaro ^{[4
]}

Takeda, Yoshio ^{[5
]}

机构：

[1] Hiroshima Univ, Grad Sch Biomed Sci, Dept Pharmacognosy, Minami Ku, Hiroshima 7348553, Japan

[2] Natl Inst Hlth Sci, Setagaya Ku, Div Novel Food & Immunochem, Tokyo 1588501, Japan

[3] Univ Ryukyus, Fac Agr, Subtrop Field Sci Ctr, Nishihara, Okinawa 9030213, Japan

[4] Tokushima Bunri Univ, Fac Pharmaceut Sci, Sanuki, Kagawa 7692193, Japan

[5] Yasuda Womens Univ, Fac Pharmaceut Sci, Asaminami Ku, Hiroshima 7310153, Japan

来源：

PHYTOCHEMISTRY | 2009年 / 70卷 / 10期

关键词：

Macaranga tanarius; Euphorbiaceae; Lignan; Megastigmane; DPPH; Cytotoxicity; MEGASTIGMANE GLYCOSIDES; GLUCOSIDES; CONSTITUENTS;

D O I：

10.1016/j.phytochem.2009.07.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A lignan glucoside, (+)-pinoresinol 4-O-[6 ''-O-galloyl]-beta-D-glucopyranoside (1), and two megastigmane glucosides, named macarangiosides E and F (2, 3), together with 15 known compounds (4-18) were isolated from leaves of Macaranga tanarius (L) Mull-Arg. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. In addition, the absolute stereochemistry of macarangiosides B and C isolated previously from the same plant was also determined for the first time. Compounds I and 2 were galloylated on glucose and possessed potent DPPH radical-scavenging activity. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1277 / 1285

页数：9

共 29 条

[1] STUDIES ON PARSONSIA .2. LIGNAN GLYCOSIDES FROM PARSONSIA-LAEVIGATA [J].