Electrocardiogram Changes as an Independent Predictive Factor of Mortality in Patients with Acute Ischemic Stroke; a Cohort Study

被引:1
作者
Asadi, Payman [1 ]
Ziabari, Seyyed Mahdi Zia [1 ]
Jahan, Donya Naghshe [1 ]
Yazdi, Arezoo Jafarian [1 ]
机构
[1] Guilan Univ Med Sci, Rd Trauma Res Ctr, Sch Med, Rasht, Iran
关键词
Stroke; brain ischemia; patient outcome assessment; electrocardiography; prognosis; emergency service; hospital; ECG ABNORMALITIES; HEART-DISEASE; UPDATE;
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Introduction: Various factors such as age and severity of the stroke have been deemed connected with risk of mortality in patients with acute ischemic brain stroke. The present study was performed with the aim of evaluating the role of electrocardiogram (ECG) changes in predicting the outcome of these patients. Methods: In this cohort study, patients who had presented to the emergency department of a teaching hospital during 1 year and were diagnosed with acute ischemic stroke were evaluated. Demographic data and 12-lead ECG findings of the patients were gathered and their relationship with 1-year mortality was analyzed. Results: Finally, 546 stroke patients with the mean age of 69.5 +/- 12.7 (24 - 100) years were studied (53.3% female). 82.7% of the studied patients had at least one of the evaluated ECG abnormalities. The most conunon ECG findings included normal sinus rhythm (27.3%), inverted T wave (21.2%), sinus tachycardia (11.7%), atrial fibrillation (AF) (11.5%), and pathologic Q wave (9.9%). In the end, 117 (20.9%) patients died during the 1-year follow-up. Frequencies of non-sinus rhythm (p < 0.0001), inverted T wave (p = 0.0001), AF rhythm (p<0.0001), pathologic Q (p<0.0001), ST segment changes (p = 0.011), and atrioventricular (AV) node block (p = 0.007) were significantly higher in patients who died. ECG changes increased the odds of 1-year mortality of these patients 4 times (Odds ratio = 4.05 with 95% CI: 2.39 - 6.87; p < 0.0001). Additionally, age over 60 years and having a history of cardiac diseases increased the odds of mortality 6 (95% CI: 1.4 - 27.9) and 1.5 (95% CI: 0.9 - 2.1) times, respectively. Conclusion: Based on the findings of the present study, it seems that along with age and history of cardiac diseases, ECG changes can be considered as an independent predictive factor of mortality in patients with ischemic stroke.
引用
收藏
页数:5
相关论文
共 21 条
[1]   ECG abnormalities and stroke incidence [J].
Agarwal, Sunil K. ;
Soliman, Elsayed Z. .
EXPERT REVIEW OF CARDIOVASCULAR THERAPY, 2013, 11 (07) :853-861
[2]  
Bozluolcay M, 2003, NEUROL INDIA, V51, P500
[3]   Insular lesions, ECG abnormalities, and outcome in acute stroke [J].
Christensen, H ;
Boysen, G ;
Christensen, AF ;
Johannesen, HH .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2005, 76 (02) :269-271
[4]   Abnormalities on ECG and telemetry predict stroke outcome at 3 months [J].
Christensen, H ;
Christensen, AF ;
Boysen, G .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2005, 234 (1-2) :99-103
[5]  
EBRAHIM K, 2012, J APPL RES CLIN EXP, V12, P53
[6]   Stroke in developing countries: can the epidemic be stopped and outcomes improved? [J].
Feigin, Valery L. .
LANCET NEUROLOGY, 2007, 6 (02) :94-97
[7]   Heart Disease and Stroke Statistics-2013 Update A Report From the American Heart Association [J].
Go, Alan S. ;
Mozaffarian, Dariush ;
Roger, Veronique L. ;
Benjamin, Emelia J. ;
Berry, Jarett D. ;
Borden, William B. ;
Bravata, Dawn M. ;
Dai, Shifan ;
Ford, Earl S. ;
Fox, Caroline S. ;
Franco, Sheila ;
Fullerton, Heather J. ;
Gillespie, Cathleen ;
Hailpern, Susan M. ;
Heit, John A. ;
Howard, Virginia J. ;
Huffman, Mark D. ;
Kissela, Brett M. ;
Kittner, Steven J. ;
Lackland, Daniel T. ;
Lichtman, Judith H. ;
Lisabeth, Lynda D. ;
Magid, David ;
Marcus, Gregory M. ;
Marelli, Ariane ;
Matchar, David B. ;
McGuire, Darren K. ;
Mohler, Emile R. ;
Moy, Claudia S. ;
Mussolino, Michael E. ;
Nichol, Graham ;
Paynter, Nina P. ;
Schreiner, Pamela J. ;
Sorlie, Paul D. ;
Stein, Joel ;
Turan, Tanya N. ;
Virani, Salim S. ;
Wong, Nathan D. ;
Woo, Daniel ;
Turner, Melanie B. .
CIRCULATION, 2013, 127 (01) :E6-E245
[8]   ELECTROCARDIOGRAM IN STROKE - RELATIONSHIP TO PATHOPHYSIOLOGICAL TYPE AND COMPARISON WITH PRIOR TRACINGS [J].
GOLDSTEIN, DS .
STROKE, 1979, 10 (03) :253-259
[9]   Hypertension prevalence, awareness, treatment and control in national surveys from England, the USA and Canada, and correlation with stroke and ischaemic heart disease mortality: a cross-sectional study [J].
Joffres, Michel ;
Falaschetti, Emanuela ;
Gillespie, Cathleen ;
Robitaille, Cynthia ;
Loustalot, Fleetwood ;
Poulter, Neil ;
McAlister, Finlay A. ;
Johansen, Helen ;
Baclic, Oliver ;
Campbell, Norm .
BMJ OPEN, 2013, 3 (08)
[10]   Electrocardiographic changes in patients with acute stroke: A systematic review [J].
Khechinashvili, G ;
Asplund, K .
CEREBROVASCULAR DISEASES, 2002, 14 (02) :67-76