Tyrosine Kinase Inhibitor Use and Wound Healing in Tracheoesophageal Punctures

被引：5

作者：

Britt, Christopher J. ^{[1
]}

Russell, Jonathon O. ^{[2
]}

机构：

[1] Loyola Univ, Med Ctr, Dept Otolaryngol, Chicago, IL 60611 USA

[2] Johns Hopkins Univ, Dept Otolaryngol, 601 N Caroline St,JHOC 6th Floor, Baltimore, MD 21287 USA

来源：

ENT-EAR NOSE & THROAT JOURNAL | 2019年 / 98卷 / 08期

关键词：

TEP; wound healing; tracheoesophageal fistula; tyrosine kinase inhibitor; TKI; laryngectomy; prosthesis; biologics; thyroid cancer; thyroid carcinoma; thyroidectomy; GROWTH-FACTOR; CANCER; VOICE;

D O I：

10.1177/0145561319839805

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Tyrosine kinase inhibitors (TKIs) aid in prolonging life in patients with advanced locoregional thyroid malignancy. Such patients may undergo total laryngectomy for local disease control and tracheoesophageal puncture (TEP) for speech rehabilitation. Enlargement of TEP fistulas is usually attributed to wound healing issues and leads to major complications. Four laryngectomies with TEP were performed between 2015 and 2016 and subsequently placed on a TKI. Three patients developed a complication after TKI treatment, and 2 patients had a tracheoesophageal fistula. Patients should be counseled about possible wound healing risks associated with TKIs.

引用

页码：510 / 512

页数：3

共 19 条

[1]

ANDREWS JC, 1987, LARYNGOSCOPE, V97, P562

[2] The Role of Vascular Endothelial Growth Factor in Wound Healing [J].

Bao, Philip ;

Kodra, Arber ;

Tomic-Canic, Marjana ;

Golinko, Michael S. ;

Ehrlich, H. Paul ;

Brem, Harold .

JOURNAL OF SURGICAL RESEARCH, 2009, 153 (02) :347-358

[3] Comparison between Primary and Secondary Tracheoesophageal Puncture Prosthesis: A Systematic Review [J].

Barauna Neto, Jose Carlos ;

Dedivitis, Rogerio Aparecido ;

Aires, Felipe Toyama ;

Pfann, Robert Zasawadzki ;

Matos, Leandro Luongo ;

Cernea, Claudio Roberto .

ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY HEAD AND NECK SURGERY, 2017, 79 (04) :222-229

[4] Effect of Age on the Efficacy and Safety of Lenvatinib in Radioiodine-Refractory Differentiated Thyroid Cancer in the Phase III SELECT Trial [J].

Brose, Marcia S. ;

Worden, Francis P. ;

Newbold, Kate L. ;

Guo, Matthew ;

Hurria, Arti .

JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (23) :2692-+

[5] Primary versus secondary tracheoesophageal puncture: systematic review and meta-analysis [J].

Chakravarty, P. D. ;

McMurran, A. E. L. ;

Banigo, A. ;

Shakeel, M. ;

Wah-See, K. .

JOURNAL OF LARYNGOLOGY AND OTOLOGY, 2018, 132 (01) :14-21

[6] TRACHEOESOPHAGEAL PUNCTURE - A REVIEW OF PROBLEMS AND COMPLICATIONS [J].

GARTH, RJN ;

MCRAE, A ;

EVANS, PHR .

JOURNAL OF LARYNGOLOGY AND OTOLOGY, 1991, 105 (09) :750-754

[7] Surgical outcomes and complications associated with presurgical tyrosine kinase inhibition for advanced renal cell carcinoma (RCC) [J].

Harshman, Lauren C. ;

Yu, R. James ;

Allen, Genevera I. ;

Srinivas, Sandy ;

Gill, Harcharan S. ;

Chung, Benjamin I. .

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2013, 31 (03) :379-385

[8] Sorafenib in Japanese Patients with Locally Advanced or Metastatic Medullary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma [J].

Ito, Yasuhiro ;

Onoda, Naoyoshi ;

Ito, Ken-ichi ;

Sugitani, Iwao ;

Takahashi, Shunji ;

Yamaguchi, Iku ;

Kabu, Koki ;

Tsukada, Katsuya .

THYROID, 2017, 27 (09) :1142-1148

[9] Trends in Thyroid Cancer Incidence and Mortality in the United States, 1974-2013 [J].

Lim, Hyeyeun ;

Devesa, Susan S. ;

Sosa, Julie A. ;

Check, David ;

Kitahara, Cari M. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2017, 317 (13) :1338-1348

[10] Primary versus secondary tracheoesophageal puncture for voice rehabilitation in laryngectomy patients: A systematic review [J].

Luu, K. ;

Chang, B. A. ;

Valenzuela, D. ;

Anderson, D. .

CLINICAL OTOLARYNGOLOGY, 2018, 43 (05) :1250-1259

← 1 2 →