Mapping quantitative trait loci regulating chicken body composition traits

被引：24
作者：
Gao, Y. [1 ]
Du, Z. Q. [1 ]
Wei, W. H. [2 ]
Yu, X. J. [3 ]
Deng, X. M. [4 ]
Feng, C. G. [1 ]
Fei, J. [1 ]
Feng, J. D. [1 ]
Li, N. [1 ]
Hu, X. X. [1 ]
机构：
[1] China Agr Univ, State Key Lab Agrobiotechnol, Beijing 100094, Peoples R China
[2] Western Gen Hosp, MRC Human Genet Unit, Edinburgh EH4 2XU, Midlothian, Scotland
[3] Shandong Agr Univ, Coll Anim Sci & Technol, Tai An 271018, Shandong, Peoples R China
[4] China Agr Univ, Coll Anim Sci & Technol, Beijing 100094, Peoples R China
来源：
ANIMAL GENETICS | 2009年 / 40卷 / 06期
基金：
英国生物技术与生命科学研究理事会; 中国国家自然科学基金;
关键词：
body composition traits; chicken; genome scan; quantitative trait loci; BROILER LAYER CROSS; WEIGHT;
D O I：
10.1111/j.1365-2052.2009.01911.x
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
P>Genome scans were conducted on an F-2 resource population derived from intercross of the White Plymouth Rock with the Silkies Fowl to detect QTL affecting chicken body composition traits. The population was genotyped with 129 microsatellite markers and phenotyped for 12 body composition traits on 238 F-2 individuals from 15 full-sib families. In total, 21 genome-wide QTL were found to be responsible for 11 traits, including two newly studied traits of proventriculus weight and shank girth. Three QTL were genome-wide significant: at 499 cm on GGA1 (explained 3.6% of phenotypic variance, P < 0.01) and 51 cm on GGA5 (explained 3.3% of phenotypic variance, P < 0.05) for the shank & claw weight and 502 cm on GGA1 (explained 1.4% of phenotypic variance, P < 0.05) for wing weight. The QTL on GGA1 seemed to have pleiotropic effects, also affecting gizzard weight at 490 cm, shank girth at 489 cm and intestine length at 481 cm. It is suggested that further efforts be made to understand the possible pleiotropic effects of the QTL on GGA1 and that on GGA5 for two shank-related traits.
引用
收藏
页码：952 / 954
页数：3
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