A rapid screening battery to identify frontal dysfunction in patients with ALS

被引:42
作者
Flaherty-Craig, Claire [1 ]
Eslinger, Paul [1 ]
Stephens, Beth [1 ]
Simmons, Zachary [1 ]
机构
[1] Penn State Univ, Milton S Hershey Med Ctr, Dept Neurol, Penn State Coll Med, Hershey, PA 17033 USA
关键词
D O I
10.1212/01.wnl.0000247667.89251.43
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We studied the relationship between verbal associative fluency, verbal abstract reasoning, and judgment in ALS using a 20-minute screening evaluation. Deficiencies in these measures were found in 20.0%, 18.6%, and 35.7% of patients with limb-onset ALS and in 37.5%, 25.0%, and 60.0% of patients with bulbar-onset ALS. This simple screen identifies deficits that affect discussions of treatment interventions and end-of-life issues.
引用
收藏
页码:2070 / 2072
页数:3
相关论文
共 10 条
  • [1] Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS)
    Abrahams, S
    Leigh, PN
    Harvey, A
    Vythelingum, GN
    Grisé, D
    Goldstein, LH
    [J]. NEUROPSYCHOLOGIA, 2000, 38 (06) : 734 - 747
  • [2] [Anonymous], 1995, COGNISTAT NEUROBEHAV
  • [3] Benton A. L., 1989, Multilingual aphasia examination
  • [4] El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis
    Brooks, BR
    Miller, RG
    Swash, M
    Munsat, TL
    [J]. AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS, 2000, 1 (05): : 293 - 299
  • [5] Brooks BR, 1996, ARCH NEUROL-CHICAGO, V53, P141
  • [6] Frontotemporal lobar degeneration - A consensus on clinical diagnostic criteria
    Neary, D
    Snowden, JS
    Gustafson, L
    Passant, U
    Stuss, D
    Black, S
    Freedman, M
    Kertesz, A
    Robert, PH
    Albert, M
    Boone, K
    Miller, BL
    Cummings, J
    Benson, DF
    [J]. NEUROLOGY, 1998, 51 (06) : 1546 - 1554
  • [7] DEMENTIA - ESTIMATION OF PREMORBID INTELLIGENCE LEVELS USING NEW ADULT READING TEST
    NELSON, HE
    OCONNELL, A
    [J]. CORTEX, 1978, 14 (02) : 234 - 244
  • [8] Prevalence and patterns of cognitive impairment in sporadic ALS
    Ringholz, GM
    Appel, SH
    Bradshaw, M
    Cooke, NA
    Mosnik, DM
    Schulz, PE
    [J]. NEUROLOGY, 2005, 65 (04) : 586 - 590
  • [9] SHALLICE T, 1991, FRONTAL LOBE FUNCTION AND DYSFUNCTION, P125
  • [10] Progress in clinical neurosciences: The evidence for ALS as a multisystems disorder of limited phenotypic expression
    Strong, MJ
    [J]. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2001, 28 (04) : 283 - 298