Air-Stable Manganese(I)-Catalyzed C-H Activation for Decarboxylative C-H/C-O Cleavages in Water

被引：164

作者：

Wang, Hui ^{[1
]}

Lorion, Melanie M. ^{[1
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Georg August Univ Gottingen, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2017年 / 56卷 / 22期

基金：

欧洲研究理事会;

关键词：

amino acids; C-H activation; C-O cleavage; heterocycles; imines; manganese; CARBON-CARBON BONDS; AMINO-ACIDS; MANGANESE; FUNCTIONALIZATION; ARENES; ALLYLATION; ALKYNES; DIVERSIFICATION; ARYLATION; PEPTIDES;

D O I：

10.1002/anie.201702193

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The decarboxylative C-H/C-O functionalization was accomplished by air-and water-tolerant manganese(I) catalysis. The versatile C-H allylation occurred by facile organometallic C-H metalation on indoles, arenes, amino acids and synthetically meaningful aryl ketimines with ample substrate scope and high levels of chemo-, site- and regioselectivity.

引用

页码：6339 / 6342

页数：4

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