Poly (styrene-divinyl benzene-glycidylmethacrylate) stationary phase grafted with poly amidoamine (PAMAM) dendrimers for rapid determination of phenylene diamine isomers in HPLC

被引：25

作者：

Guo, Dandan ^{[1
]}

Lou, Chaoyan ^{[1
]}

Wang, Nani ^{[1
,4
]}

Chen, Meilan ^{[3
]}

Zhang, Peimin ^{[1
]}

Wu, Shuchao ^{[2
]}

Zhu, Yan ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Xixi Campus, Hangzhou 310028, Peoples R China

[2] Zhejiang Inst Geol & Mineral Resources, Hangzhou 310007, Zhejiang, Peoples R China

[3] Zhejiang Shuren Univ, Coll Biol & Environm Engn, Hangzhou 310015, Zhejiang, Peoples R China

[4] Zhejiang Acad Tradit Chinese Med, Dept Med, Hangzhou, Zhejiang, Peoples R China

来源：

TALANTA | 2017年 / 168卷

基金：

美国国家科学基金会;

关键词：

HPLC column; Grafted stationary phase; Poly amidoamine dendrimers; Phenylene diamine isomers; Hair dye precursors; P-PHENYLENEDIAMINE; HAIR-DYES; ELECTROCHEMICAL DETECTION; LIQUID-CHROMATOGRAPHY; SILICA MICROSPHERES; MASS-SPECTROMETRY; AROMATIC-AMINES; VALIDATION; STABILITY; ELECTROPHORESIS;

D O I：

10.1016/j.talanta.2017.03.053

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel high performance liquid stationary phase was prepared by grafting poly amidoamine (PAMAM) dendrimers to poly (styrene-divinyl benzene-glycidylmethacrylate) matrix in this work. Different generations of PAMAM dendrimers grafted to polymer matrices containing different glycidylmethacrylate amounts by reacting with epoxy groups in glycidylmethacrylate molecules. The synthesized PAMAM dendrimers and stationary phase were characterized by fourier transform infrared spectroscopy, scanning electron microscope, N-2 adsorption/desorption, elemental analysis and thermo gravimetric analyzer. The proposed stationary phase was suitable for rapid separation of phenylene diamine isomers and aminobenzene. The separation mechanism of benzene rings attraction and amino repulsion was verified by retention behaviors of methylamine, phenylamine, phenylene diamine, naphthylamine and toluene. The reliability of the stationary phase was demonstrated by separation and determination of phenylene diamine isomers including m-phenylene diamine, o-phenylene diamine and p-phenylene diamine in hair dye precursors within 10 min. Satisfactory resolution and short analysis time make the columns promising for determination of aniline compounds in various fields.

引用

页码：188 / 195

页数：8

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