Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: A retrospective cohort study of 137 children with sickle cell anemia

被引：101

作者：

Hulbert, Monica L.

Scothorn, Douglas J.

Panepinto, Julie A.

Scott, J. Paul

Buchanan, George R.

Sarnaik, Sharada

Fallon, Robert

Chu, Jen-Yih

Wang, Winfred

Casella, James F.

Resar, Linda

Berman, Brian

Adamkiewicz, Thomas

Hsu, Lewis L.

Smith-Whitley, Kimberly

Mahoney, Donald

Woods, Gerald

Watanabe, Masayo

DeBaun, Michael R.

机构：

[1] Washington Univ, Sch Med, St Louis, MO 63108 USA

[2] Univ Texas, SW Med Ctr, Dallas, TX 75230 USA

[3] Childrens Hosp Michigan, Detroit, MI 48201 USA

[4] Med Coll Wisconsin, Milwaukee, WI 53226 USA

[5] Cardinal Glennon Mem Hosp Children, St Louis, MO 63104 USA

[6] St Jude Childrens Hosp, Memphis, TN 38105 USA

[7] Rainbow Babies & Childrens Hosp, Cleveland, OH 44106 USA

[8] Johns Hopkins Univ, Sch Med, Baltimore, MD USA

[9] Emory Univ, Sch Med, Atlanta, GA 30322 USA

[10] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA

[11] Baylor Coll Med, Houston, TX 77030 USA

[12] Univ Missouri, Kansas City, MO 64110 USA

来源：

JOURNAL OF PEDIATRICS | 2006年 / 149卷 / 05期

关键词：

D O I：

10.1016/j.jpeds.2006.06.037

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A retrospective cohort study of children with sickle cell anemia (SCA) and strokes was used to test the hypothesis that exchange transfusion at the time of stroke presentation more effectively prevents second strokes than does simple transfusion. Children receiving simple transfusion had a 5-fold greater relative risk (95% confidence interval = 1.3 to 18.6) of second stroke than those receiving exchange transfusion.

引用

页码：710 / 712

页数：3

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