Cardiovascular Calcium Channel Blockers: Historical Overview, Development and New Approaches in Design

被引：16

作者：

Drapak, Iryna ^{[1
]}

Perekhoda, Lina ^{[2
]}

Tsapko, Tetiana ^{[2
]}

Berezniakova, Natalia ^{[2
]}

Tsapko, Yevgen ^{[3
]}

机构：

[1] Lvivskyj Nacl Nyj Med Univ Imeni Danyla Halyckoho, Dept Gen Bioinorgan Phys & Colloidal Chem, UA-58666 Lvov, Ukraine

[2] Nacl Farmacevtychnyj Univ, Dept Med Chem, UA-199318 Kharkov, Ukraine

[3] Nacl Farmacevtychnyj Univ, Dept Inorgan Chem, UA-199318 Kharkov, Ukraine

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2017年 / 54卷 / 04期

关键词：

II RECEPTOR BLOCKER; BLOOD-PRESSURE; BIOLOGICAL EVALUATION; HYPERTENSIVE PATIENTS; CONVERTING-ENZYME; DERIVATIVES; MODULATORS; ANTAGONIST; DRUGS; DIHYDROPYRIDINES;

D O I：

10.1002/jhet.2837

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The data on historical development and modern design approaches for calcium channels blockers (mainly L-type) are summarized in this review. Chemical groups such as dihydropyridine and hydropyrimidine derivatives, as well as phenylalkylamines and benzothiazepines are discussed.

引用

页码：2117 / 2128

页数：12

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