Simple equations to predict the effects of veno-venous ECMO in decompensated Eisenmenger syndrome

被引：1

作者：

Bonnemain, Jean ^{[1
,2
]}

Auberson, Denise ^{[2
,3
]}

Rutz, Tobias ^{[2
,3
]}

Yerly, Patrick ^{[2
,3
]}

Aubert, John-David ^{[2
,4
]}

Roumy, Aurelien ^{[2
,5
]}

Pantet, Olivier ^{[1
,2
]}

Rusca, Marco ^{[1
,2
]}

Liaudet, Lucas ^{[1
,2
]}

Piquilloud, Lise ^{[1
,2
]}

机构：

[1] Univ Lausanne, Univ Hosp, Serv Adult Intens Care Med, Rue Bugnon 46, CH-1011 Lausanne, Switzerland

[2] Univ Lausanne, Fac Biol & Med, Rue Bugnon 46, CH-1011 Lausanne, Switzerland

[3] Univ Lausanne, Univ Hosp, Serv Cardiol, Rue Bugnon 46, CH-1011 Lausanne, Switzerland

[4] Univ Lausanne, Univ Hosp, Serv Pneumol, Rue Bugnon 46, CH-1011 Lausanne, Switzerland

[5] Univ Lausanne, Univ Hosp, Serv Cardiac Surg, Rue Bugnon 46, CH-1011 Lausanne, Switzerland

来源：

ESC HEART FAILURE | 2021年 / 8卷 / 02期

关键词：

Extracorporeal membrane oxygenation; ECMO; Veno-venous; Hypoxaemia; Eisenmenger syndrome;

D O I：

10.1002/ehf2.13253

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Adult patients with uncorrected congenital heart diseases and chronic intracardiac shunt may develop Eisenmenger syndrome (ES) due to progressive increase of pulmonary vascular resistance, with significant morbidity and mortality. Acute decompensation of ES in conditions promoting a further increase of pulmonary vascular resistance, such as pulmonary embolism or pneumonia, can precipitate major arterial hypoxia and death. In such conditions, increasing systemic oxygenation with veno-venous extracorporeal membrane oxygenation (VV-ECMO) could be life-saving, serving as a bridge to treat a potential reversible cause for the decompensation, or to urgent lung transplantation. Anticipating the effects of VV-ECMO in this setting could ease the clinical decision to initiate such therapeutic strategy. Here, we present a series of equations to accurately predict the effects of VV-ECMO on arterial oxygenation in ES and illustrate this point by a case of ES decompensation with refractory hypoxaemia consecutive to an acute respiratory failure due to viral pneumonia.

引用

页码：1637 / 1642

页数：6

共 12 条

[1] Eisenmenger syndrome: diagnosis, prognosis and clinical management [J].