Modification of the Membrane Components of Synaptosomes and the Fusion Process

被引：0
作者：
Tsyvkin, V. [1 ]
Prudnikov, I. [1 ]
Kastrykina, T. [1 ]
Kolchinskaya, L. [1 ]
Malysheva, M. [1 ]
机构：
[1] Natl Acad Sci Ukraine, Bogomolets Inst Physiol, Kiev, Ukraine
来源：
NEUROPHYSIOLOGY | 2002年 / 34卷 / 2-3期
关键词：
exocytosis; fusion; synaptosomes; membrane modification; nitric oxide;
D O I：
10.1023/A:1020748626882
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A model system consisting of synaptic vesicles and synaptic membrane fragments isolated from brain synaptosomes was used for studying the role of the state of membrane components in membrane fusion. It is concluded that the state of proteins and lipids of biological membranes influences considerably the membrane's ability to fuse. This state can be changed by the regulation of cell enzyme systems (proteolytic enzymes, phospholipases), and regulation by nitric oxide is an important aspect of this control.
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收藏
页码：250 / 251
页数：2
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