Magnetic resonance imaging of the retina

被引:28
作者
Duong, Timothy Q. [1 ,2 ,3 ,4 ,5 ]
Muir, Eric R. [1 ,6 ]
机构
[1] Univ Texas Hlth Sci Ctr San Antonio, Res Imaging Ctr, Dept Ophthalmol, San Antonio, TX 78229 USA
[2] Univ Texas Hlth Sci Ctr San Antonio, Res Imaging Ctr, Dept Radiol, San Antonio, TX 78229 USA
[3] Univ Texas Hlth Sci Ctr San Antonio, Res Imaging Ctr, Dept Physiol, San Antonio, TX 78229 USA
[4] S Texas Vet Hlth Care Syst, San Antonio, TX USA
[5] SW Natl Primate Res Ctr, San Antonio, TX USA
[6] Georgia Inst Technol, Grad Program Biomed Engn, Atlanta, GA 30332 USA
关键词
blood flow; blood oxygenation level-dependent (BOLD); fMRI; oxygenation; retinal diseases; CEREBRAL-BLOOD-FLOW; HIGH-RESOLUTION; FUNCTIONAL MRI; SOMATOSENSORY STIMULATION; QUANTITATIVE PERFUSION; LAMINAR SPECIFICITY; OXYGEN-CONSUMPTION; MACAQUE RETINA; OPTIC-NERVE; BRAIN;
D O I
10.1007/s10384-009-0688-1
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
This paper reviews recent developments in high-resolution magnetic resonance imaging (MRI) and its application to image anatomy, physiology, and function in the retina of animals. It describes technical issues and solutions in performing retinal MRI, anatomical MRI, blood oxygenation level-dependent functional MRI (fMRI), and blood-flow MRI both of normal retinas and of retinal degeneration. MRI offers unique advantages over existing retinal imaging techniques, including the ability to image multiple layers without depth limitation and to provide multiple clinically relevant data in a single setting. Retinal MRI has the potential to complement existing retinal imaging techniques.
引用
收藏
页码:352 / 367
页数:16
相关论文
共 87 条
[1]   BLOOD FLOW AND OXYGEN EXTRACTION IN CAT UVEA AT NORMAL AND HIGH INTRAOCULAR PRESSURES [J].
ALM, A ;
BILL, A .
ACTA PHYSIOLOGICA SCANDINAVICA, 1970, 80 (01) :19-&
[2]   OCULAR AND OPTIC-NERVE BLOOD-FLOW AT NORMAL AND INCREASED INTRAOCULAR PRESSURES IN MONKEYS (MACACA-IRUS) - STUDY WITH RADIOACTIVELY LABELED MICROSPHERES INCLUDING FLOW DETERMINATIONS IN BRAIN AND SOME SOME OTHER TISSUES [J].
ALM, A ;
BILL, A .
EXPERIMENTAL EYE RESEARCH, 1973, 15 (01) :15-29
[3]   Reduced transit-time sensitivity in noninvasive magnetic resonance imaging of human cerebral blood flow [J].
Alsop, DC ;
Detre, JA .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1996, 16 (06) :1236-1249
[4]  
Ball S, 2003, ADV EXP MED BIOL, V533, P181
[5]   TIME COURSE EPI OF HUMAN BRAIN-FUNCTION DURING TASK ACTIVATION [J].
BANDETTINI, PA ;
WONG, EC ;
HINKS, RS ;
TIKOFSKY, RS ;
HYDE, JS .
MAGNETIC RESONANCE IN MEDICINE, 1992, 25 (02) :390-397
[6]   Noninvasive and simultaneous imaging of layer-specific retinal functional adaptation by manganese-enhanced MRI [J].
Berkowitz, Bruce A. ;
Roberts, Robin ;
Goebel, Dennis J. ;
Luan, Hongmei .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2006, 47 (06) :2668-2674
[8]  
Bill A, 1984, HDB PHYSL CARDIOVASC, P1001
[9]  
Bron A.J., 1997, WOLFFS ANATOMY EYE O
[10]   HOW THICK SHOULD A RETINA BE - A COMPARATIVE-STUDY OF MAMMALIAN-SPECIES WITH AND WITHOUT INTRARETINAL VASCULATURE [J].
BUTTERY, RG ;
HINRICHSEN, CFL ;
WELLER, WL ;
HAIGHT, JR .
VISION RESEARCH, 1991, 31 (02) :169-&