Detection of Dural Metastases Before the Onset of Clinical Symptoms by 16α-[18F]Fluoro-17β-Estradiol PET in a Patient With Estrogen Receptor-Positive Breast Cancer

被引：8
作者：
Boers, Jorianne [1 ]
Schroder, Carolina P. [1 ]
Hospers, Geke A. P. [1 ]
de Vries, Erik F. J. [2 ]
Glaudemans, Andor W. J. M. [2 ]
机构：
[1] Univ Groningen, Univ Med Ctr Groningen, Dept Med Oncol, Groningen, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Nucl Med & Mol Imaging, Groningen, Netherlands
来源：
CLINICAL NUCLEAR MEDICINE | 2021年 / 46卷 / 03期
关键词：
F-18]-FES PET; brain metastases; breast cancer; estrogen receptor;
D O I：
10.1097/RLU.0000000000003382
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We offer an illustrative case about estrogen receptor (ER) imaging (also known as 16 alpha-[F-18]fluoro-17 beta-estradiol ([F-18]-FES) PET) and the detection of metastatic lesions in the dural region. We present a case of a woman with ER-positive metastatic breast cancer and high [F-18]-FES uptake in the dural region on PET imaging, without associated clinical symptoms. These lesions were missed on [F-18]-FDG PET because of physiological [F-18]-FDG uptake in the brain. This case highlighted some difficulties in the interpretation of imaging of brain metastases and demonstrated the added value of [F-18]-FES PET imaging. [F-18]-FES PET could be used to prove the presence of ER-positive metastases in the brain.
引用
收藏
页码：e165 / e167
页数：3
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