Signal transduction from multiple Ras effectors

被引：273
作者：
Katz, ME [1 ]
McCormick, F [1 ]
机构：
[1] ONYX PHARMACEUT, RICHMOND, CA 94806 USA
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1997年 / 7卷 / 01期
关键词：
D O I：
10.1016/S0959-437X(97)80112-8
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Ras proteins activate a signaling cascade through direct binding of the serine/threonine kinase Raf. They also activate additional signaling pathways that are essential for full biological activity. Candidate effecters for these pathways include RalGDS and phosphatidyl inositol 3' kinase, as well as several other Ras binding proteins the biochemical and biological properties of which are poorly understood.
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页码：75 / 79
页数：5
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