Mapping of 59 EST gene markers in 31 intervals spanning the human X chromosome

被引：10
作者：
Gianfrancesco, F
Esposito, T
Ruini, L
Houlgatte, R
Nagaraja, R
DEsposito, M
Rocchi, M
Auffray, C
Schlessinger, D
DUrso, M
Forabosco, A
机构：
[1] CNR,INT INST GENET & BIOPHYS,I-80125 NAPLES,ITALY
[2] UNIV MODENA,DIPARTIMENTO SCI MORFOL & MEDICOLEGALI,SEZ ISTOL EMBRIOL & GENET,I-41100 MODENA,ITALY
[3] CNRS,UPR 420,F-94801 VILLEJUIF,FRANCE
[4] WASHINGTON UNIV,SCH MED,DEPT MOL MICROBIOL,ST LOUIS,MO 63110
[5] IST GENET,I-70126 BARI,ITALY
来源：
GENE | 1997年 / 187卷 / 02期
关键词：
human genome; somatic cell hybrid; X physical and genetic map; X-linked disease;
D O I：
10.1016/S0378-1119(96)00743-3
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The positioning of Expressed Sequence Tags (ESTs) constitutes an important step towards a functional map of the human genome, including candidate genes for human genetic disorders that have been localized by linkage analysis. We localized 59 ESTs on the human X chromosome, including 44 derived from infant brain and 15 from adult muscle cDNA libraries. Localizations by a somatic cell hybrid panel were refined for five cDNAs by mapping them in yeast artificial chromosome (YAC) contigs.
引用
收藏
页码：179 / 184
页数：6
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