Evaluation of serum ischaemia-modified albumin levels in patients with Bell's palsy

被引：2
作者：
Goker, A. E. [1 ]
Alagoz, M. H. [2 ]
Guntas, G. [3 ]
Yilmazer, A. Baskadem [1 ]
Berkiten, G. [1 ]
Tutar, B. [1 ]
Ekincioglu, M. E. [1 ]
Akgun, M. F. [1 ]
Uyar, Y. [1 ]
Ozdemir, E. [1 ]
机构：
[1] Univ Hlth Sci, Okmeydani Training & Res Hosp, Dept Otorhinolaryngol Head & Neck Surg, Istanbul, Turkey
[2] Univ Hlth Sci, Okmeydani Training & Res Hosp, Dept Biochem, Istanbul, Turkey
[3] Kirklareli Univ, Sch Hlth, Kirklareli, Turkey
来源：
JOURNAL OF LARYNGOLOGY AND OTOLOGY | 2019年 / 133卷 / 09期
关键词：
Facial Nerve; Bell Palsy; Ischemia-Modified Albumin;
D O I：
10.1017/S0022215119001683
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Objective This prospective study aimed to evaluate the relationship between serum ischaemia-modified albumin levels and Bell's palsy severity. Methods The study included 30 patients diagnosed with Bell's palsy and 30 healthy individuals. The patients were separated into three disease severity groups (grades 2, 3 and 4) according to House-Brackmann classification. Blood samples were collected from all participants and the results compared between groups. Results Significant differences in serum ischaemia-modified albumin were found between the study and control groups (p < 0.001); values were significantly higher in the study group than in the control group. Conclusion The significantly higher levels of serum ischaemia-modified albumin in the study group suggest that Bell's palsy pathogenesis is associated with oxidative stress.
引用
收藏
页码：810 / 813
页数：4
相关论文
共 20 条
[1]   Thiol/disulphide homeostasis in Bell's palsy as a novel pathogenetic marker [J].
Babademez, M. A. ;
Gul, F. ;
Kale, H. ;
Muderris, T. ;
Bayazit, Y. ;
Ergin, M. ;
Erel, O. ;
Kiris, M. .
CLINICAL OTOLARYNGOLOGY, 2017, 42 (02) :239-244
[2]   Clinical Practice Guideline: Bell's Palsy [J].
Baugh, Reginald F. ;
Basura, Gregory J. ;
Ishii, Lisa E. ;
Schwartz, Seth R. ;
Drumheller, Caitlin Murray ;
Burkholder, Rebecca ;
Deckard, Nathan A. ;
Dawson, Cindy ;
Driscoll, Colin ;
Gillespie, M. Boyd ;
Gurgel, Richard K. ;
Halperin, John ;
Khalid, Ayesha N. ;
Kumar, Kaparaboyna Ashok ;
Micco, Alan ;
Munsell, Debra ;
Rosenbaum, Steven ;
Vaughan, William .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2013, 149 :S1-S27
[3]   Prognostic factors of Bell's palsy and Ramsay Hunt syndrome [J].
Cai, Zhengyi ;
Li, Huijing ;
Wang, Xun ;
Niu, Xiaoting ;
Ni, Peiqi ;
Zhang, Wanli ;
Shao, Bei .
MEDICINE, 2017, 96 (02)
[4]  
Can U, 2017, KOSUYOLU HEART J, V20, P148, DOI [10.5578/khj.10257, DOI 10.5578/KHJ.10257]
[5]   Utility of admission cardiac troponin and "Ischemia Modified Albumin" measurements for rapid evaluation and rule out of suspected acute myocardial infarction in the emergency department [J].
Collinson, PO ;
Gaze, DC ;
Bainbridge, K ;
Morris, F ;
Morris, B ;
Price, A ;
Goodacre, S .
EMERGENCY MEDICINE JOURNAL, 2006, 23 (04) :256-261
[6]   Ischemia Modified Albumin Levels and Oxidative Stress in Patients with Bladder Cancer [J].
Ellidag, Hamit Yasar ;
Eren, Esin ;
Aydin, Ozgur ;
Akgol, Evren ;
Yalcinkaya, Soner ;
Sezer, Cem ;
Yilmaz, Necat .
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2013, 14 (05) :2759-2763
[7]   Association between ischemia-modified albumin, homocysteine, vitamin B12 and folic acid in patients with severe sepsis [J].
Erdem, Said Sami ;
Yerlikaya, Fatma Humeyra ;
Cicekler, Humeyra ;
Gul, Mehmet .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2012, 50 (08) :1417-1421
[8]   Increased ischemia-modified albumin levels in patients with gastric cancer [J].
Fidan, E. ;
Mentese, A. ;
Kavgaci, H. ;
Orem, A. ;
Fidan, S. ;
Uzun, A. ;
Ozdemir, F. ;
Aydin, F. .
NEOPLASMA, 2012, 59 (04) :393-397
[9]   Ischemia Modified Albumin: A Novel Biomarker for the Detection of Cardiac Ischemia [J].
Gaze, David C. .
DRUG METABOLISM AND PHARMACOKINETICS, 2009, 24 (04) :333-341
[10]   Bell's palsy: a summary of current evidence and referral algorithm [J].
Glass, Graeme E. ;
Tzafetta, Kallirroi .
FAMILY PRACTICE, 2014, 31 (06) :631-642
12