Selective platination of modified oligonucleotides and duplex cross-links

被引：14
作者：
Alguero, Berta
de la Osa, Jaime Lopez
Gonzalez, Carlos
Pedroso, Enrique
Marchan, Vicente
Grandas, Anna
机构：
[1] Univ Barcelona, Fac Quim, Dept Quim Organ, E-08028 Barcelona, Spain
[2] CSIC, Inst Quim Fis Rocasolano, E-28006 Madrid, Spain
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 48期
关键词：
cross-links; imidazoles; oligonucleotides; platinum; thioethers;
D O I：
10.1002/anie.200603128
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Stabilizing strands: Selectively cross-linked duplexes can be obtained either by hybridization-promoted rearrangement of platinated oligonucleotides or by annealing thioether- and imidazole-modified oligonucleotides and their complementary chains in the presence of transplatin (see structure). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：8194 / 8197
页数：4
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