Positron Emission Tomography in oncology: Present and future of PET and PET/CT

被引:35
作者
Papathanassiou, Dimitri [1 ,4 ]
Bruna-Muraille, Claire [1 ,4 ,6 ]
Liehn, Jean-Claude [1 ,4 ]
Nguyen, Tan Dat [2 ,4 ,5 ]
Cure, Herve [3 ,4 ]
机构
[1] Inst Jean Godinot, Nucl Med Serv, F-51056 Reims, France
[2] Inst Jean Godinot, Dept Radiotherapie, F-51056 Reims, France
[3] Inst Jean Godinot, Dept Med Oncol, F-51056 Reims, France
[4] Univ Reims, UFR Med, Reims, France
[5] Inst Jean Godinot, Radiat Dept, F-51056 Reims, France
[6] Univ Reims, Dept Biophys & Nucl Med, Reims, France
关键词
PET; PET/CT; Imaging; Oncology; SQUAMOUS-CELL CARCINOMA; COLORECTAL LIVER METASTASES; STANDARDIZED UPTAKE VALUES; LYMPH-NODE METASTASES; SMALL ANIMAL PET; BODY FDG PET; F-18-FDG PET; LUNG-CANCER; DIAGNOSTIC-ACCURACY; COMPUTED-TOMOGRAPHY;
D O I
10.1016/j.critrevonc.2008.10.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PET is a crucial technique in molecular imaging, allowing in vivo assessment and localization of pathological processes, thanks to its ability to detect very small amounts of radioactive molecules. This is of particular interest in oncology where abnormal metabolism or synthesis in tumor cells but also various tumor characteristics can be studied using this nuclear medicine technique. FDG is currently the most widely used tracer, nowadays essential in the management of various malignancies, with large applications in diagnosis, initial assessment, therapy monitoring, and recurrence detection. The combination of anatomical information provided by PET/CT further increased its interest. Beyond its spread use in daily practice, future applications of PET will involve other tracers than FDG and develop research applications in humans as well as in small animals. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:239 / 254
页数:16
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