[1] Sunnybrook Res Inst, Phys Sci, Toronto, ON, Canada
[2] Univ Toronto, Dept Med Biophys, Toronto, ON, Canada
[3] St Michaels Hosp, Keenan Res Ctr, 30 Bond St, Toronto, ON M5B 1W8, Canada
[4] St Michaels Hosp, Div Neurosurg, 30 Bond St, Toronto, ON M5B 1W8, Canada
[5] St Michaels Hosp, Dept Anesthesia, 30 Bond St, Toronto, ON M5B 1W8, Canada
[6] Harvard Univ, Sch Med, Athinoula A Martinos Ctr Biomed Imaging, Boston, MA USA