Outcomes of patients with COVID-19 hospitalized during the fourth pandemic wave in relation to their clinical features and vaccination status

被引：0

作者：

Crivellari, Stefania ^{[1
]}

Pasquali, Mercedes ^{[2
]}

Aiosa, Giuseppe ^{[3
]}

Daniele, Antonio ^{[4
]}

Bertolotti, Marinella ^{[1
]}

Salerno, Christian ^{[1
]}

Pacileo, Guglielmo ^{[5
]}

Marchisio, Sara ^{[6
]}

Maconi, Antonio ^{[1
]}

Gnerre, Paola ^{[4
]}

机构：

[1] Azienda Osped SS Antonio & Biagio & Cesare Arrigo, Res Training Innovat Infrastruct Res & Innovat De, Alessandria, Italy

[2] Presidio Osped S Spirito, ASL AL, SC Pneumol, Casale Monferrato, AL, Italy

[3] Presidio Osped S Spirito, ASL AL, SC Internal Med, Casale Monferrato, AL, Italy

[4] ASL AL, Dept Internal Med, Acqui Terme, AL, Italy

[5] ASL AL, Res & Innovat Dept DAIRI, Ctr Hlth Management Studies, Alessandria, Italy

[6] ASL AL, Hlth Dept, Alessandria, Italy

来源：

ITALIAN JOURNAL OF MEDICINE | 2022年 / 16卷 / 01期

关键词：

COVID-19; pandemic; vaccine; vaccination;

D O I：

10.4081/itjm.2022.1541

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study aims to observe the clinical characteristics and outcomes of recovered patients from coronavirus disease 2019 (COVID-19) related to the vaccination status. We examined results of 205 COVID-19-recovered patients from 15 December 2021 to 1 March 2022 in two hospitals of Local Health Authority of Alessandria (Italy) during the fourth pandemic wave. 77% of patients were hospitalized for acute respiratory failure (ARF) with radiological pneumonia pattern (recovered for COVID), 23% for other causes with occasional positivity finding (recovered with COVID). 32% of patients were not vaccinated for SARS-CoV-2, 37% had three doses, 25% two doses, 5% only one dose. All patients without vaccination were hospitalized for ARF and they had a 7 times higher risk of hospitalization than the vaccinated. 60% of all patients had =3 comorbidities, of these 50% was vaccinated with three doses. In the fourth pandemic wave compared to the other not all patients were hospitalized for ARF and pneumonia and the presence of comorbidities >= 3 is a risk factor for hospitalization regardless of vaccination status. This justifies the administration of the fourth dose to frail patients.

引用

页数：6